Methyl 4,5-diamino-2-fluorobenzoate

Base Information

Chemical Name:Methyl 4,5-diamino-2-fluorobenzoate
CAS No.:936939-69-4
Molecular Formula:C₈H₉FN₂O₂
Molecular Weight:184.17
Hs Code.:
European Community (EC) Number:844-536-0

Synonyms:METHYL 4,5-DIAMINO-2-FLUOROBENZOATE;936939-69-4;SCHEMBL1509484;FADJCISTXVQLMQ-UHFFFAOYSA-N;WS-00835;METHYL4,5-DIAMINO-2-FLUOROBENZOATE;W19189;EN300-1699048

Suppliers and Price of Methyl 4,5-diamino-2-fluorobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl4,5-diamino-2-fluorobenzoate 97%
250mg
$ 554.00

Crysdot
Methyl4,5-diamino-2-fluorobenzoate 97%
100mg
$ 277.00

Chemcia Scientific
4,5-Diamino-2-fluoro-benzoicacidmethylester 95%
1 G
$ 560.00

Alichem
Methyl4,5-diamino-2-fluorobenzoate
25g
$ 4020.00

Alichem
Methyl4,5-diamino-2-fluorobenzoate
10g
$ 2532.60

Alichem
Methyl4,5-diamino-2-fluorobenzoate
5g
$ 1768.80

AK Scientific
Methyl4,5-diamino-2-fluorobenzoate
2.5g
$ 1683.00

Total 2 raw suppliers

Chemical Property of Methyl 4,5-diamino-2-fluorobenzoate

Chemical Property:

Boiling Point:389.8±42.0 °C(Predicted)
Density:1.353±0.06 g/cm3(Predicted)
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:184.06480570
Heavy Atom Count:13
Complexity:201

Purity/Quality:

98% ^*data from raw suppliers

Methyl4,5-diamino-2-fluorobenzoate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CC(=C(C=C1F)N)N

Technology Process of Methyl 4,5-diamino-2-fluorobenzoate

There total 3 articles about Methyl 4,5-diamino-2-fluorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 872871-50-6
methyl 4-amino-2-fluoro-5-nitrobenzoate

: 936939-69-4
methyl 4,5-diamino-2-fluorobenzoate

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; for 20h;

Reference yield:

: methyl 4-(tert-butylamino)-2-fluoro-5-nitrobenzoate

: 936939-69-4
methyl 4,5-diamino-2-fluorobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C

2: palladium 10% on activated carbon; hydrogen / methanol / 3 h

With palladium 10% on activated carbon; hydrogen; trifluoroacetic acid; In methanol; dichloromethane;

Reference yield:

: 125568-71-0
methyl 2,4-difluoro-5-nitrobenzoate

: 936939-69-4
methyl 4,5-diamino-2-fluorobenzoate

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 0 - 20 °C

2: trifluoroacetic acid / dichloromethane / 3 h / 20 °C

3: palladium 10% on activated carbon; hydrogen / methanol / 3 h

With palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane;