Propionic acid, 3-(2,2-dimethyl-1-aziridinyl)-, methyl ester

Base Information

• Chemical Name: Propionic acid, 3-(2,2-dimethyl-1-aziridinyl)-, methyl ester
• CAS No.: 25263-40-5
• Molecular Formula: C₈H₁₅NO₂
• Molecular Weight: 157.213
• NSC Number: 115805
• UNII: QWZ83C9IKJ
• Nikkaji Number: J92.666C
• Mol file: 25263-40-5.mol

Synonyms:QWZ83C9IKJ;25263-40-5;Propionic acid, 3-(2,2-dimethyl-1-aziridinyl)-, methyl ester;NSC-115805;NSC 115805;BRN 0120087;(2,2-Dimethylaziridine)propionic acid, methyl ester;NSC115805;3-(2,2-Dimethyl-1-aziridinyl)propionic acid methyl ester;UNII-QWZ83C9IKJ;4-20-00-00283 (Beilstein Handbook Reference);1-AZIRIDINEPROPANOIC ACID, 2,2-DIMETHYL-, METHYL ESTER;1-AZIRIDINEPROPIONIC ACID, 2,2-DIMETHYL-, METHYL ESTER

Chemical Property of Propionic acid, 3-(2,2-dimethyl-1-aziridinyl)-, methyl ester

Chemical Property:

• Vapor Pressure: 0.483mmHg at 25°C
• Boiling Point: 192.7°C at 760 mmHg
• Flash Point: 77.3°C
• Density: 1.002g/cm³
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 157.110278721
• Heavy Atom Count: 11
• Complexity: 166

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(CN1CCC(=O)OC)C

Technology Process of Propionic acid, 3-(2,2-dimethyl-1-aziridinyl)-, methyl ester

There total 1 articles about Propionic acid, 3-(2,2-dimethyl-1-aziridinyl)-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2-dimethylaziridine (2658-24-4) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → 3-(2,2-dimethyl-aziridin-1-yl)-propionic acid methyl ester (25263-40-5)

Guidance literature:

DOI:10.1021/ja01137a020

Reference yield:

3-(2,2-dimethyl-aziridin-1-yl)-propionic acid methyl ester (25263-40-5) → 1-(2,2-dimethyl-aziridin-1-yl)-3-phenylcarbamoyloxy-propane

Guidance literature:

Multi-step reaction with 2 steps

1: lithium alanate; diethyl ether

2: hexane

With lithium aluminium tetrahydride; diethyl ether; hexane;

DOI:10.1021/ja01137a020

Reference yield:

3-(2,2-dimethyl-aziridin-1-yl)-propionic acid methyl ester (25263-40-5) → (4-phenylazo-phenyl)-carbamic acid-[3-(2,2-dimethyl-aziridin-1-yl)-propyl ester]

Guidance literature:

Multi-step reaction with 2 steps

1: lithium alanate; diethyl ether

2: benzene

With lithium aluminium tetrahydride; diethyl ether; benzene;

DOI:10.1021/ja01137a020

upstream raw materials:

2,2-dimethylaziridine

acrylic acid methyl ester