octahydro-9-hydroxyethyl-1-methoxy-3,4,4-trimethyl-1H-3,9a-peroxy-2-benzoxepin

Base Information

• Chemical Name: octahydro-9-hydroxyethyl-1-methoxy-3,4,4-trimethyl-1H-3,9a-peroxy-2-benzoxepin
• CAS No.: 156382-50-2
• Molecular Formula: C₁₆H₂₈O₅
• Molecular Weight: 300.395
• Mol file: 156382-50-2.mol

Synonyms:3,9a-(Epoxymethano)-9aH-1,2-benzodioxepin-9-ethanol,octahydro-10-methoxy-3,4,4-trimethyl-, (3a,5ab,9a,9aa,10S*)-(?à)-

Chemical Property of octahydro-9-hydroxyethyl-1-methoxy-3,4,4-trimethyl-1H-3,9a-peroxy-2-benzoxepin

Chemical Property:

• Vapor Pressure: 3.52E-07mmHg at 25°C
• Boiling Point: 375.6°Cat760mmHg
• Flash Point: 181°C
• Density: 1.15g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of octahydro-9-hydroxyethyl-1-methoxy-3,4,4-trimethyl-1H-3,9a-peroxy-2-benzoxepin

There total 1 articles about octahydro-9-hydroxyethyl-1-methoxy-3,4,4-trimethyl-1H-3,9a-peroxy-2-benzoxepin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyllithium (917-54-4) + 3-{(1R,3S)-3-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[1-methoxy-meth-(E)-ylidene]-cyclohexyl}-2,2-dimethyl-propionitrile → 2-((1R,2S,6R,9R,12S)-12-Methoxy-8,8,9-trimethyl-10,11,13-trioxa-tricyclo[7.2.2.01,6]tridec-2-yl)-ethanol (156382-50-2)

Guidance literature:

With t-butyldimethylsiyl triflate; tetrabutyl ammonium fluoride; oxygen; triethylamine; Yield given. Multistep reaction;

DOI:10.1021/jm00035a003

upstream raw materials:

methyllithium