(1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-(4-fluorophenyl)but-3-en-2-yl benzoate

Base Information

Chemical Name:(1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-(4-fluorophenyl)but-3-en-2-yl benzoate
CAS No.:1198053-73-4
Molecular Formula:C₂₁H₂₄FNO₃S
Molecular Weight:389.491
Hs Code.:

Synonyms:(1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-(4-fluorophenyl)but-3-en-2-yl benzoate

Suppliers and Price of (1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-(4-fluorophenyl)but-3-en-2-yl benzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-(4-fluorophenyl)but-3-en-2-yl benzoate

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Technology Process of (1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-(4-fluorophenyl)but-3-en-2-yl benzoate

There total 1 articles about (1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-(4-fluorophenyl)but-3-en-2-yl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1267688-18-5
(R)-N-(4-fluorobenzylidene)-2-methylpropane-2-sulfinamide

: 500756-90-1
(E)-3-bromoprop-1-enyl benzoate

: 1198053-73-4
(1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-(4-fluorophenyl)but-3-en-2-yl benzoate

Guidance literature:: With zinc; In N,N,N,N,N,N-hexamethylphosphoric triamide; water; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1002/chem.200900801

Reference yield:

: 1198053-73-4
(1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-(4-fluorophenyl)but-3-en-2-yl benzoate

: 108-24-7
acetic anhydride

: 1198053-94-9
C₁₉H₁₈FNO₃

Guidance literature:: (1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-(4-fluorophenyl)but-3-en-2-yl benzoate; With hydrogenchloride; methanol; at 20 ℃;

acetic anhydride; With dmap; triethylamine; In dichloromethane; at 20 ℃; optical yield given as %ee;
DOI:10.1002/chem.200900801