5-Methyl-2-((4R,4'S,4''S)-4,4',4''-trimethyl-4,5,4',5',4'',5''-hexahydro-[2,4';2',4'']terthiazol-4-yl)-oxazole-4-carboxylic acid methylamide

Base Information

• Chemical Name: 5-Methyl-2-((4R,4'S,4''S)-4,4',4''-trimethyl-4,5,4',5',4'',5''-hexahydro-[2,4';2',4'']terthiazol-4-yl)-oxazole-4-carboxylic acid methylamide
• CAS No.: 257278-52-7
• Molecular Formula: C₁₈H₂₃N₅O₂S₃
• Molecular Weight: 437.611

Synonyms:5-Methyl-2-((4R,4'S,4''S)-4,4',4''-trimethyl-4,5,4',5',4'',5''-hexahydro-[2,4';2',4'']terthiazol-4-yl)-oxazole-4-carboxylic acid methylamide

Chemical Property of 5-Methyl-2-((4R,4'S,4''S)-4,4',4''-trimethyl-4,5,4',5',4'',5''-hexahydro-[2,4';2',4'']terthiazol-4-yl)-oxazole-4-carboxylic acid methylamide

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Technology Process of 5-Methyl-2-((4R,4'S,4''S)-4,4',4''-trimethyl-4,5,4',5',4'',5''-hexahydro-[2,4';2',4'']terthiazol-4-yl)-oxazole-4-carboxylic acid methylamide

There total 1 articles about 5-Methyl-2-((4R,4'S,4''S)-4,4',4''-trimethyl-4,5,4',5',4'',5''-hexahydro-[2,4';2',4'']terthiazol-4-yl)-oxazole-4-carboxylic acid methylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

(-)-Thiangazole (138667-71-7,144370-38-7) → 5-Methyl-2-((4R,4'S,4''S)-4,4',4''-trimethyl-4,5,4',5',4'',5''-hexahydro-[2,4';2',4'']terthiazol-4-yl)-oxazole-4-carboxylic acid methylamide (257278-52-7) + 2-((4R,4'S,4''S)-2''-Formyl-4,4',4''-trimethyl-4,5,4',5',4'',5''-hexahydro-[2,4';2',4'']terthiazol-4-yl)-5-methyl-oxazole-4-carboxylic acid methylamide (257278-51-6) + thiangazole 19,19-dioxide + C36H48N10O6S6

Guidance literature:

With osmium(VIII) oxide; 4-methylmorpholine N-oxide; In water; acetone; tert-butyl alcohol; at 20 ℃; for 7h;

DOI:10.1002/(SICI)1099-0690(199912)1999:12<3381::AID-EJOC3381>3.0.CO;2-W

upstream raw materials:

(-)-Thiangazole

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