6-[{5-[(7-chloroquinolin-4-yl)amino]-2-hydroxybenzyl}(ethyl)amino]hexane-1,2-diyl dinitrate

Base Information

Chemical Name:6-[{5-[(7-chloroquinolin-4-yl)amino]-2-hydroxybenzyl}(ethyl)amino]hexane-1,2-diyl dinitrate
CAS No.:1300743-18-3
Molecular Formula:C₂₄H₂₈ClN₅O₇
Molecular Weight:533.969
Hs Code.:

Synonyms:6-[{5-[(7-chloroquinolin-4-yl)amino]-2-hydroxybenzyl}(ethyl)amino]hexane-1,2-diyl dinitrate

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Chemical Property of 6-[{5-[(7-chloroquinolin-4-yl)amino]-2-hydroxybenzyl}(ethyl)amino]hexane-1,2-diyl dinitrate

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Technology Process of 6-[{5-[(7-chloroquinolin-4-yl)amino]-2-hydroxybenzyl}(ethyl)amino]hexane-1,2-diyl dinitrate

There total 2 articles about 6-[{5-[(7-chloroquinolin-4-yl)amino]-2-hydroxybenzyl}(ethyl)amino]hexane-1,2-diyl dinitrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1203701-93-2
2-chloromethyl-4-[(7-chloroquinolin-4-yl)amino]phenol hydrochloride

: 1300743-14-9
N-ethyl-5,6-bis(nitrooxy)hexan-1-ammonium nitrate

: 1300743-18-3
6-[{5-[(7-chloroquinolin-4-yl)amino]-2-hydroxybenzyl}(ethyl)amino]hexane-1,2-diyl dinitrate

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; acetonitrile; at 0 - 20 ℃;
DOI:10.1016/j.ejmech.2011.02.029

Reference yield:

: 1300743-12-7
6-(ethylamino)hexane-1,2-diol

: 1300743-18-3
6-[{5-[(7-chloroquinolin-4-yl)amino]-2-hydroxybenzyl}(ethyl)amino]hexane-1,2-diyl dinitrate

Guidance literature:: Multi-step reaction with 2 steps

1: nitric acid / -15 - 20 °C

2: triethylamine / N,N-dimethyl-formamide; acetonitrile / 0 - 20 °C

With nitric acid; triethylamine; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.ejmech.2011.02.029