5-(4-Fluoro-phenyl)-4-imino-7-p-tolyl-4,7-dihydro-pyrrolo[2,3-d]pyrimidin-3-ylamine

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Chemical Name:5-(4-Fluoro-phenyl)-4-imino-7-p-tolyl-4,7-dihydro-pyrrolo[2,3-d]pyrimidin-3-ylamine
CAS No.:204271-32-9
Molecular Formula:C₁₉H₁₆FN₅
Molecular Weight:333.368
Hs Code.:

Synonyms:5-(4-Fluoro-phenyl)-4-imino-7-p-tolyl-4,7-dihydro-pyrrolo[2,3-d]pyrimidin-3-ylamine

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Chemical Property of 5-(4-Fluoro-phenyl)-4-imino-7-p-tolyl-4,7-dihydro-pyrrolo[2,3-d]pyrimidin-3-ylamine

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Technology Process of 5-(4-Fluoro-phenyl)-4-imino-7-p-tolyl-4,7-dihydro-pyrrolo[2,3-d]pyrimidin-3-ylamine

There total 2 articles about 5-(4-Fluoro-phenyl)-4-imino-7-p-tolyl-4,7-dihydro-pyrrolo[2,3-d]pyrimidin-3-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 204271-30-7
N-[3-Cyano-4-(4-fluoro-phenyl)-1-p-tolyl-1H-pyrrol-2-yl]-formimidic acid ethyl ester

: 204271-32-9
5-(4-Fluoro-phenyl)-4-imino-7-p-tolyl-4,7-dihydro-pyrrolo[2,3-d]pyrimidin-3-ylamine

Guidance literature:: With hydrazine hydrate; In ethanol; for 20h; Ambient temperature;

Reference yield:

: 170464-69-4
2-amino-4-(4-fluorophenyl)-1-(p-tolyl)pyrrole-3-carbonitrile

: 204271-32-9
5-(4-Fluoro-phenyl)-4-imino-7-p-tolyl-4,7-dihydro-pyrrolo[2,3-d]pyrimidin-3-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / Ac₂O, TFA / 3 h / Heating

2: 75 percent / 80percent NH₂NH₂*H₂O / ethanol / 20 h / Ambient temperature

With acetic anhydride; hydrazine hydrate; trifluoroacetic acid; In ethanol;