(S)-3'-Hydroxy-N-Methylcoclaurine Hydrochloride

Base Information

• Chemical Name: (S)-3'-Hydroxy-N-Methylcoclaurine Hydrochloride
• CAS No.: 138644-99-2
• Molecular Formula: C₁₈H₂₁NO₄*ClH
• Molecular Weight: 351.83
• Mol file: 138644-99-2.mol

Synonyms:(+)-(S)-1-<3',4'-dihyroxybenzyl>-1,2,3,4-tetrahydro-6-methoxy-2-methylisoquinolin-7-ol hydrochloride

Chemical Property of (S)-3'-Hydroxy-N-Methylcoclaurine Hydrochloride

Chemical Property:

• Melting Point: 138-141°C
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly, Sonicated)

Purity/Quality:

99% ^*data from raw suppliers

(S)-3’-Hydroxy-N-methylcoclaurineHydrochloride(~75%ee) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: (S)-3’-Hydroxy-N-methylcoclaurine is an structure analog of Coclaurine (C633550), a benzyltetrahydroisoquinoline alkaloid extracted from Magnolia salicifolia.

Technology Process of (S)-3'-Hydroxy-N-Methylcoclaurine Hydrochloride

There total 1 articles about (S)-3'-Hydroxy-N-Methylcoclaurine Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.8%

(+)-(S)-1-<3',4'-bis(benzyloxy)benzyl>-1,2,3,4-tetrahydro-6-methoxy-2-methylisoquinolin-7-ol oxalate (138645-08-6) → (+)-(S)-1-<3',4'-dihyroxybenzyl>-1,2,3,4-tetrahydro-6-methoxy-2-methylisoquinolin-7-ol hydrochloride (138644-99-2)

Guidance literature:

With hydrogenchloride; hydrogen; palladium dihydroxide; In ethanol; Ambient temperature;

DOI:10.1002/hlca.19910740704

upstream raw materials:

(+)-(S)-1-<3',4'-bis(benzyloxy)benzyl>-1,2,3,4-tetrahydro-6-methoxy-2-methylisoquinolin-7-ol oxalate

Refernces