5-tert-butyl-5-methyl-1,3-oxazolidin-2-one

Base Information

Chemical Name:5-tert-butyl-5-methyl-1,3-oxazolidin-2-one
CAS No.:29558-57-4
Molecular Formula:C₈H₁₅NO₂
Molecular Weight:157.213
Hs Code.:
Mol file:29558-57-4.mol

Synonyms:2-Oxazolidinone,5-tert-butyl-5-methyl- (8CI); NSC 171613

Suppliers and Price of 5-tert-butyl-5-methyl-1,3-oxazolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of 5-tert-butyl-5-methyl-1,3-oxazolidin-2-one

Chemical Property:

Vapor Pressure:0.003mmHg at 25°C
Boiling Point:284.3°C at 760 mmHg
Flash Point:125.8°C
Density:1.001g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-tert-butyl-5-methyl-1,3-oxazolidin-2-one

There total 5 articles about 5-tert-butyl-5-methyl-1,3-oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 2,3,3-trimethylbutan-2-yl benzoyloxycarbamate

: 29558-57-4
5-(tert-butyl)-5-methyloxazolidin-2-one

Guidance literature:: With C₃₄H₁₈F₁₀IrN₄^(1-)*F₆P⁽¹⁺⁾; N-ethyl-N,N-diisopropylamine; (4S,4S')-(-)-2,2'-(1-methylethylidene)bis[4,5-dihydro-4-(phenylmethyl)oxazole]; nickel dichloride; In acetonitrile; at 30 ℃; for 5h; chemoselective reaction; Schlenk technique; Inert atmosphere; Irradiation;
DOI:10.1021/acs.orglett.8b03299

Reference yield:

: 3938-95-2
2,2-dimethyl-propanoic acid ethyl ester

: 29558-57-4
5-(tert-butyl)-5-methyloxazolidin-2-one

Guidance literature:: Multi-step reaction with 4 steps

1: palladium 10% on activated carbon / diethyl ether; toluene / 0 °C / Inert atmosphere

2: toluene / 60 °C

3: triethylamine / tetrahydrofuran / 0 °C

4: nickel dichloride; N-ethyl-N,N-diisopropylamine; (4S,4S')-(-)-2,2'-(1-methylethylidene)bis[4,5-dihydro-4-(phenylmethyl)oxazole]; C₃₄H₁₈F₁₀IrN₄^(1-)*F₆P⁽¹⁺⁾ / acetonitrile / 5 h / 30 °C / Schlenk technique; Inert atmosphere; Irradiation

With palladium 10% on activated carbon; C₃₄H₁₈F₁₀IrN₄^(1-)*F₆P⁽¹⁺⁾; triethylamine; N-ethyl-N,N-diisopropylamine; (4S,4S')-(-)-2,2'-(1-methylethylidene)bis[4,5-dihydro-4-(phenylmethyl)oxazole]; nickel dichloride; In tetrahydrofuran; diethyl ether; toluene; acetonitrile;
DOI:10.1021/acs.orglett.8b03299

Reference yield:

: 594-83-2
2,3,3-trimethyl-2-butanol

: 29558-57-4
5-(tert-butyl)-5-methyloxazolidin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: toluene / 60 °C

2: triethylamine / tetrahydrofuran / 0 °C

3: nickel dichloride; N-ethyl-N,N-diisopropylamine; (4S,4S')-(-)-2,2'-(1-methylethylidene)bis[4,5-dihydro-4-(phenylmethyl)oxazole]; C₃₄H₁₈F₁₀IrN₄^(1-)*F₆P⁽¹⁺⁾ / acetonitrile / 5 h / 30 °C / Schlenk technique; Inert atmosphere; Irradiation

With C₃₄H₁₈F₁₀IrN₄^(1-)*F₆P⁽¹⁺⁾; triethylamine; N-ethyl-N,N-diisopropylamine; (4S,4S')-(-)-2,2'-(1-methylethylidene)bis[4,5-dihydro-4-(phenylmethyl)oxazole]; nickel dichloride; In tetrahydrofuran; toluene; acetonitrile;
DOI:10.1021/acs.orglett.8b03299