Methyl 4-[1-[(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)methyl]propyl]benzoate

Base Information

Chemical Name:Methyl 4-[1-[(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)methyl]propyl]benzoate
CAS No.:425663-94-1
Molecular Formula:C₁₈H₂₀N₄O₃
Molecular Weight:340.382
Hs Code.:
DSSTox Substance ID:DTXSID601147154

Synonyms:DTXSID601147154;Methyl 4-[1-[(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)methyl]propyl]benzoate;425663-94-1

Suppliers and Price of Methyl 4-[1-[(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)methyl]propyl]benzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Methyl 4-[1-[(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)methyl]propyl]benzoate

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:340.15354051
Heavy Atom Count:25
Complexity:456

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC(CC1=COC2=NC(=NC(=C12)N)N)C3=CC=C(C=C3)C(=O)OC

Technology Process of Methyl 4-[1-[(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)methyl]propyl]benzoate

There total 1 articles about Methyl 4-[1-[(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)methyl]propyl]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: methyl (E/Z)-4-[1-ethyl-2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethenyl]benzoate

: 425663-94-1
methyl (R/S)-4-[1-ethyl-2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethyl]benzoate

Guidance literature:: With hydrogen; 10percent Pd/C; In methanol; chloroform; at 20 ℃; for 8h; under 2327.23 Torr;
DOI:10.1021/jm010575m

Reference yield: 95.0%

: 425663-94-1
methyl (R/S)-4-[1-ethyl-2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethyl]benzoate

: 425663-98-5
(R/S)-4-[1-ethyl-2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid

Guidance literature:: With sodium hydroxide; In methanol; dimethyl sulfoxide; at 20 ℃; for 16h;
DOI:10.1021/jm010575m

Reference yield:

: 425663-94-1
methyl (R/S)-4-[1-ethyl-2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethyl]benzoate

: C₂₂H₂₆N₄O₅

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / aq. NaOH / methanol; dimethylsulfoxide / 16 h / 20 °C

2: Et₃N / dimethylformamide / 0.5 h / 0 °C

With sodium hydroxide; triethylamine; In methanol; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1021/jm010575m