N-((2S,3S)-3-trans-ethoxycarbonyloxiran-2-carbonyl)-L-leucine benzyl amide

Base Information

Chemical Name:N-((2S,3S)-3-trans-ethoxycarbonyloxiran-2-carbonyl)-L-leucine benzyl amide
CAS No.:159086-42-7
Molecular Formula:C₁₉H₂₆N₂O₅
Molecular Weight:362.426
Hs Code.:

Synonyms:N-((2S,3S)-3-trans-ethoxycarbonyloxiran-2-carbonyl)-L-leucine benzyl amide

Suppliers and Price of N-((2S,3S)-3-trans-ethoxycarbonyloxiran-2-carbonyl)-L-leucine benzyl amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-((2S,3S)-3-trans-ethoxycarbonyloxiran-2-carbonyl)-L-leucine benzyl amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-((2S,3S)-3-trans-ethoxycarbonyloxiran-2-carbonyl)-L-leucine benzyl amide

There total 2 articles about N-((2S,3S)-3-trans-ethoxycarbonyloxiran-2-carbonyl)-L-leucine benzyl amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3291-46-1,3291-47-2,61937-48-2,66647-17-4,74243-85-9,73890-18-3
(2S,3S)-diethyl oxirane-2,3-dicarboxylate

: 159086-42-7
N-((2S,3S)-3-trans-ethoxycarbonyloxiran-2-carbonyl)-L-leucine benzyl amide

Guidance literature:: Multi-step reaction with 2 steps

1: 57.7 percent / 0.1M aq. KH₂PO₄, 1M aq. NaOH / 20 °C / pig liver esterase

2: 1.) DCC, 2.) HOBt / 1.) THF, 0.5 h, 2.) THF, a) -5 deg C, 1 h, b) 25 deg C, 2 d

With sodium hydroxide; potassium dihydrogenphosphate; benzotriazol-1-ol; dicyclohexyl-carbodiimide;
DOI:10.1006/bioo.1994.1017

Reference yield:

: 63734-73-6,66647-16-3,68521-71-1,89886-73-7,93061-20-2,149884-11-7
ethyl (2S,3S)-2,3-epoxysuccinate

: 80152-39-2
(S)-2-amino-N-benzyl-4-methylpentanamide

: 159086-42-7
N-((2S,3S)-3-trans-ethoxycarbonyloxiran-2-carbonyl)-L-leucine benzyl amide

Guidance literature:: With benzotriazol-1-ol; dicyclohexyl-carbodiimide; Yield given. Multistep reaction; 1.) THF, 0.5 h, 2.) THF, a) -5 deg C, 1 h, b) 25 deg C, 2 d;
DOI:10.1006/bioo.1994.1017