Technology Process of C21H20
There total 5 articles about C21H20 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
water; sodium hydroxide;
In
methanol; diethyl ether;
at 20 ℃;
for 0.5h;
DOI:10.3762/bjoc.7.58
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere
1.2: 3 h / 20 °C / Inert atmosphere
2.1: triethylsilane; trifluoroacetic acid
3.1: copper(l) iodide; bis(triphenylphosphine)palladium(II) dichloride; triethylamine / toluene / 5 h / 70 °C
4.1: water; sodium hydroxide / methanol; diethyl ether / 0.5 h / 20 °C
With
triethylsilane; copper(l) iodide; bis(triphenylphosphine)palladium(II) dichloride; water; triethylamine; trifluoroacetic acid; sodium hydroxide; lithium diisopropyl amide;
In
tetrahydrofuran; methanol; diethyl ether; toluene;
3.1: Sonogashira reaction;
DOI:10.3762/bjoc.7.58
- Guidance literature:
-
Multi-step reaction with 3 steps
1: triethylsilane; trifluoroacetic acid
2: copper(l) iodide; bis(triphenylphosphine)palladium(II) dichloride; triethylamine / toluene / 5 h / 70 °C
3: water; sodium hydroxide / methanol; diethyl ether / 0.5 h / 20 °C
With
triethylsilane; copper(l) iodide; bis(triphenylphosphine)palladium(II) dichloride; water; triethylamine; trifluoroacetic acid; sodium hydroxide;
In
methanol; diethyl ether; toluene;
2: Sonogashira reaction;
DOI:10.3762/bjoc.7.58
