1-Ethoxycarbonylamino-5-methyl-2-oxo-3,4-diphenyl-2,3-dihydroimidazole

Base Information

• Chemical Name: 1-Ethoxycarbonylamino-5-methyl-2-oxo-3,4-diphenyl-2,3-dihydroimidazole
• CAS No.: 79359-25-4
• Molecular Formula: C₁₉H₁₉N₃O₃
• Molecular Weight: 337.378
• Mol file: 79359-25-4.mol

Synonyms:1-Ethoxycarbonylamino-5-methyl-2-oxo-3,4-diphenyl-2,3-dihydroimidazole

Chemical Property of 1-Ethoxycarbonylamino-5-methyl-2-oxo-3,4-diphenyl-2,3-dihydroimidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Ethoxycarbonylamino-5-methyl-2-oxo-3,4-diphenyl-2,3-dihydroimidazole

There total 2 articles about 1-Ethoxycarbonylamino-5-methyl-2-oxo-3,4-diphenyl-2,3-dihydroimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

Diethyl N-(2-anilino-1-methyl-2-phenylethenyl)-hydrazine-N,N-dicarboxylate (79359-21-0) → 1-Ethoxycarbonylamino-5-methyl-2-oxo-3,4-diphenyl-2,3-dihydroimidazole (79359-25-4)

Guidance literature:

With phenyllithium; In tetrahydrofuran; diethyl ether; at 0 ℃; for 4h;

DOI:10.1055/s-1981-29530

Reference yield:

1,N-Diphenylpropanimine (14752-72-8) → 1-Ethoxycarbonylamino-5-methyl-2-oxo-3,4-diphenyl-2,3-dihydroimidazole (79359-25-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 59 percent / hexane / 2 h / Ambient temperature

2: 75 percent / C₆H₅Li / tetrahydrofuran; diethyl ether / 4 h / 0 °C

With phenyllithium; In tetrahydrofuran; diethyl ether; hexane;

DOI:10.1055/s-1981-29530

Reference yield: 80.0%

1-Ethoxycarbonylamino-5-methyl-2-oxo-3,4-diphenyl-2,3-dihydroimidazole (79359-25-4) → 1-Amino-5-methyl-2-oxo-3,4-diphenyl-2,3-dihydroimidazole (79359-29-8)

Guidance literature:

With potassium hydroxide; In ethylene glycol; for 5h; Heating;

DOI:10.1055/s-1981-29530

upstream raw materials:

Diethyl N-(2-anilino-1-methyl-2-phenylethenyl)-hydrazine-N,N-dicarboxylate

1,N-Diphenylpropanimine

Downstream raw materials:

1-Amino-5-methyl-2-oxo-3,4-diphenyl-2,3-dihydroimidazole

1-Benzylidenamino-5-methyl-2-oxo-3,4-diphenyl-2,3-dihydroimidazole