(2R,3R,4R,5R)-N-benzyloxycarbonyl-2-benzyloxymethyl-3,4-dihydroxy-5-hydroxymethylpyrrolidine

Base Information

• Chemical Name: (2R,3R,4R,5R)-N-benzyloxycarbonyl-2-benzyloxymethyl-3,4-dihydroxy-5-hydroxymethylpyrrolidine
• CAS No.: 914650-04-7
• Molecular Formula: C₂₁H₂₅NO₆
• Molecular Weight: 387.433
• Mol file: 914650-04-7.mol

Synonyms:(2R,3R,4R,5R)-N-benzyloxycarbonyl-2-benzyloxymethyl-3,4-dihydroxy-5-hydroxymethylpyrrolidine

Chemical Property of (2R,3R,4R,5R)-N-benzyloxycarbonyl-2-benzyloxymethyl-3,4-dihydroxy-5-hydroxymethylpyrrolidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3R,4R,5R)-N-benzyloxycarbonyl-2-benzyloxymethyl-3,4-dihydroxy-5-hydroxymethylpyrrolidine

There total 1 articles about (2R,3R,4R,5R)-N-benzyloxycarbonyl-2-benzyloxymethyl-3,4-dihydroxy-5-hydroxymethylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

(1R,2R,4R,5S)-N-benzyloxycarbonyl-2-benzyloxymethyl-4-hydroxymethyl-6-oxa-3-aza-bicyclo[3.1.0]hexane (914649-43-7) → (2R,3R,4R,5R)-N-benzyloxycarbonyl-2-benzyloxymethyl-3,4-dihydroxy-5-hydroxymethylpyrrolidine (914650-04-7)

Guidance literature:

With trifluoroacetic acid; In tetrahydrofuran; water; at 65 ℃; for 34h;

DOI:10.1002/chem.200600202

Reference yield:

(2R,3R,4R,5R)-N-benzyloxycarbonyl-2-benzyloxymethyl-3,4-dihydroxy-5-hydroxymethylpyrrolidine (914650-04-7) → 2,5-dideoxy-2,5-imino-D-mannitol (59920-31-9)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; for 2.5h;

DOI:10.1002/chem.200600202

upstream raw materials:

(1R,2R,4R,5S)-N-benzyloxycarbonyl-2-benzyloxymethyl-4-hydroxymethyl-6-oxa-3-aza-bicyclo[3.1.0]hexane

Downstream raw materials:

2,5-dideoxy-2,5-imino-D-mannitol