P-BROMOPHENACYLBENZOATE

Base Information

• Chemical Name: P-BROMOPHENACYLBENZOATE
• CAS No.: 7506-12-9
• Molecular Formula: C15H11BrO3
• Molecular Weight: 319.155
• Mol file: 7506-12-9.mol

Synonyms:p-Bromophenacyl benzoate;HMS2499C24;

Chemical Property of P-BROMOPHENACYLBENZOATE

Chemical Property:

• Vapor Pressure: 1.11E-08mmHg at 25°C
• Boiling Point: 461°C at 760 mmHg
• Flash Point: 232.6°C
• PSA: 43.37000
• Density: 1.454g/cm³
• LogP: 3.48880

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of P-BROMOPHENACYLBENZOATE

There total 11 articles about P-BROMOPHENACYLBENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

Potassium benzoate (582-25-2) + para-bromophenacyl bromide (99-73-0,132309-76-3) → α-(benzoyloxy)-p-bromoacetophenone (7506-12-9)

Guidance literature:

With Tris(3,6-dioxaheptyl)amine; In acetonitrile; for 0.25h; Heating;

Reference yield: 90.0%

para-bromophenacyl bromide (99-73-0,132309-76-3) + benzoic acid (65-85-0,8013-63-6) → α-(benzoyloxy)-p-bromoacetophenone (7506-12-9)

Guidance literature:

With potassium fluoride; In N,N-dimethyl-formamide; for 1.5h; Ambient temperature;

DOI:10.1021/ac50064a047

Reference yield: 88.0%

1-bromo-4-ethenyl-benzene (2039-82-9) + benzoic acid (65-85-0,8013-63-6) → α-(benzoyloxy)-p-bromoacetophenone (7506-12-9)

Guidance literature:

With tert.-butylhydroperoxide; iodine; triethylamine; In decane; dimethyl sulfoxide; at 25 ℃; for 12h; regioselective reaction; Inert atmosphere;

DOI:10.1021/ol5027393

upstream raw materials:

1-(4-bromo-phenyl)-2-diazo-ethanone

benzoic acid

sodium benzoate

para-bromophenacyl bromide

Downstream raw materials:

para-bromoacetophenone

1-(4-Dimethylaminophenylimino-)-2-keto-2-(4-bromphenyl-)-propionitril