10-dehydro-10-deacetylbaccatin III (V)

Base Information

• Chemical Name: 10-dehydro-10-deacetylbaccatin III (V)
• CAS No.: 191276-24-1
• Molecular Formula: C₂₉H₃₄O₁₀
• Molecular Weight: 542.583
• Mol file: 191276-24-1.mol

Synonyms:10-dehydro-10-deacetylbaccatin III (V)

Chemical Property of 10-dehydro-10-deacetylbaccatin III (V)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 10-dehydro-10-deacetylbaccatin III (V)

There total 2 articles about 10-dehydro-10-deacetylbaccatin III (V) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

10-deacetylbaccatin III (32981-86-5,172018-16-5) → 10-dehydro-10-deacetylbaccatin III (V) (191276-24-1)

Guidance literature:

With copper diacetate; In methanol;

DOI:10.1016/S0040-4039(97)00877-0

Reference yield: 75.0%

10-deacetylbaccatin III (32981-86-5,172018-16-5) → 10-dehydro-10-deacetylbaccatin V (151636-94-1) + 10-dehydro-10-deacetylbaccatin III (V) (191276-24-1) + 10,13-bis(dehydro)-10-deacetylbaccatin V

Guidance literature:

With copper diacetate; air; In methanol; for 72h;

DOI:10.1002/ejoc.200300376

Reference yield: 90.0%

10-dehydro-10-deacetylbaccatin III (V) (191276-24-1) → 10-dehydro-7,8-seco-10-deacetylbaccatin III

Guidance literature:

With L-Selectride; In tetrahydrofuran; for 0.05h; cooling;

DOI:10.1002/ejoc.200300376

upstream raw materials:

10-deacetylbaccatin III

Downstream raw materials:

10-deacetyl Baccatin III

10-epi-10-deacetylbaccatin V

10-deacetylbaccatin III

13-triethylsilyl-9-dihydro-10-deacetyl-10-epi-11(15->1)abeobaccatin V

Refernces

• 1、 Appendino, Giovanni,Noncovich, Alain,Bettoni, Piergiorgio,Dambruoso, Paolo,Sterner, Olov,Fontana, Gabriele,Bombardelli, Ezio. "The Reductive Fragmentation of 7-Hydroxy-9,10-dioxotaxoids". . p. 4422 - 4431. Retrieved 2007/10/03.