2-(5-phenyl-1H-pyrazol-3-yl)-3-(1H-pyrrol-2-yl)-acrylonitrile

Base Information

• Chemical Name: 2-(5-phenyl-1H-pyrazol-3-yl)-3-(1H-pyrrol-2-yl)-acrylonitrile
• CAS No.: 244216-75-9
• Molecular Formula: C₁₆H₁₂N₄
• Molecular Weight: 260.298
• Mol file: 244216-75-9.mol

Synonyms:2-(5-phenyl-1H-pyrazol-3-yl)-3-(1H-pyrrol-2-yl)-acrylonitrile

Chemical Property of 2-(5-phenyl-1H-pyrazol-3-yl)-3-(1H-pyrrol-2-yl)-acrylonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

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Technology Process of 2-(5-phenyl-1H-pyrazol-3-yl)-3-(1H-pyrrol-2-yl)-acrylonitrile

There total 2 articles about 2-(5-phenyl-1H-pyrazol-3-yl)-3-(1H-pyrrol-2-yl)-acrylonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-pyrrole aldehyde (1003-29-8,254729-95-8) + 2-(5-phenyl-1H-pyrazol-3-yl)acetonitrile (202129-57-5) → 2-(5-phenyl-1H-pyrazol-3-yl)-3-(1H-pyrrol-2-yl)-acrylonitrile (244216-75-9)

Guidance literature:

With sodium t-butanolate; In ethanol; for 5h;

DOI:10.1016/S0968-0896(99)00056-5

Reference yield: 53.0%

2-pyrrole aldehyde (1003-29-8,254729-95-8) + 2-(5-phenyl-1H-pyrazol-3-yl)acetonitrile (202129-57-5) → 2-(5-phenyl-1H-pyrazol-3-yl)-3-(1H-pyrrol-2-yl)-acrylonitrile + 2-(5-phenyl-1H-pyrazol-3-yl)-3-(1H-pyrrol-2-yl)-acrylonitrile (244216-75-9)

Guidance literature:

With sodium t-butanolate; In ethanol; for 25h; Yields of byproduct given; Heating;

DOI:10.1016/S0968-0896(99)00056-5

Reference yield:

2-(5-phenyl-1H-pyrazol-3-yl)-3-(1H-pyrrol-2-yl)-acrylonitrile (244216-75-9) → 2-(5-phenyl-1H-pyrazol-3-yl)-3-(1H-pyrrol-2-yl)-acrylonitrile

Guidance literature:

With sodium t-butanolate; In ethanol; for 24h; Yield given; Heating;

DOI:10.1016/S0968-0896(99)00056-5

upstream raw materials:

2-pyrrole aldehyde

2-(5-phenyl-1H-pyrazol-3-yl)acetonitrile