Technology Process of N'-(acridin-9-yl)-2,4-dichlorobenzohydrazide
There total 3 articles about N'-(acridin-9-yl)-2,4-dichlorobenzohydrazide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2,4 dichlorobenzoic acid;
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
tetrahydrofuran;
Cooling with ice;
(acridin-9-yl)hydrazine;
With
triethylamine;
In
tetrahydrofuran;
Cooling with ice;
DOI:10.1007/s00044-016-1581-3
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium nitrite; hydrogenchloride / water / 1 h / -5 - 0 °C
2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / tetrahydrofuran / Cooling with ice
2.2: Cooling with ice
With
hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium nitrite;
In
tetrahydrofuran; water;
DOI:10.1007/s00044-016-1581-3
- Guidance literature:
-
Entspr. 9-Chloracridin, entspr. Saeurehydrazid;
