6-(acetyloxymethyl)-9-benzylpurine

Base Information

• Chemical Name: 6-(acetyloxymethyl)-9-benzylpurine
• CAS No.: 773133-82-7
• Molecular Formula: C₁₅H₁₄N₄O₂
• Molecular Weight: 282.302
• Mol file: 773133-82-7.mol

Synonyms:6-(acetyloxymethyl)-9-benzylpurine

Chemical Property of 6-(acetyloxymethyl)-9-benzylpurine

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-(acetyloxymethyl)-9-benzylpurine

There total 2 articles about 6-(acetyloxymethyl)-9-benzylpurine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

iodomethyl acetate (13398-11-3) + 9-benzyl-6-chloro-9H-purine (1928-76-3) → 6-(acetyloxymethyl)-9-benzylpurine (773133-82-7) + 6-(hydroxymethyl)-9-benzylpurine (629604-05-3)

Guidance literature:

iodomethyl acetate; With chloro-trimethyl-silane; 1,1-Dibromoethane; zinc; In tetrahydrofuran; at 0 - 5 ℃; for 1h;

9-benzyl-6-chloro-9H-purine; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 ℃; for 8h;

DOI:10.1021/ol049059r

Reference yield: 60.0%

iodomethyl acetate (13398-11-3) + 9-benzyl-6-iodo-9H-purine (83135-13-1) → 6-(acetyloxymethyl)-9-benzylpurine (773133-82-7) + 6-(hydroxymethyl)-9-benzylpurine (629604-05-3)

Guidance literature:

iodomethyl acetate; With chloro-trimethyl-silane; 1,1-Dibromoethane; zinc; In tetrahydrofuran; at 0 - 5 ℃; for 1h;

9-benzyl-6-iodo-9H-purine; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 ℃; for 6h;

DOI:10.1021/ol049059r

Reference yield: 96.0%

6-(acetyloxymethyl)-9-benzylpurine (773133-82-7) → 6-(hydroxymethyl)-9-benzylpurine (629604-05-3)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃; for 12h;

DOI:10.1021/ol049059r

upstream raw materials:

iodomethyl acetate

9-benzyl-6-iodo-9H-purine

9-benzyl-6-chloro-9H-purine

Downstream raw materials:

6-(hydroxymethyl)-9-benzylpurine

Refernces