benzyl 2-acetamido-2-deoxy-3-O-β-D-galactopyranosyl-β-D-glucopyranoside

Base Information

• Chemical Name: benzyl 2-acetamido-2-deoxy-3-O-β-D-galactopyranosyl-β-D-glucopyranoside
• CAS No.: 80035-19-4
• Molecular Formula: C₂₁H₃₁NO₁₁
• Molecular Weight: 473.477
• Mol file: 80035-19-4.mol

Synonyms:benzyl 2-acetamido-2-deoxy-3-O-β-D-galactopyranosyl-β-D-glucopyranoside

Chemical Property of benzyl 2-acetamido-2-deoxy-3-O-β-D-galactopyranosyl-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl 2-acetamido-2-deoxy-3-O-β-D-galactopyranosyl-β-D-glucopyranoside

There total 7 articles about benzyl 2-acetamido-2-deoxy-3-O-β-D-galactopyranosyl-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

benzyl 2-acetamido-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-β-D-glucopyranoside (58902-39-9,60831-31-4) → benzyl 2-acetamido-2-deoxy-3-O-β-D-galactopyranosyl-β-D-glucopyranoside (80035-19-4)

Guidance literature:

With sodium methylate; In methanol; Ambient temperature;

DOI:10.1016/S0008-6215(00)81873-X

Reference yield:

benzyl 2-acetamido-2-deoxy-4,6-O-isopropylidene-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-β-D-glucopyranoside (80035-18-3) → benzyl 2-acetamido-2-deoxy-3-O-β-D-galactopyranosyl-β-D-glucopyranoside (80035-19-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 79 percent / acetic acid (80percent) / 0.5 h / 100 °C

2: 83 percent / sodium methoxide / methanol / Ambient temperature

With sodium methylate; acetic acid; In methanol;

DOI:10.1016/S0008-6215(00)81873-X

Reference yield:

benzyl 2-acetamido-2-deoxy-4,6-O-isopropylidene-β-D-glucopyranoside (50605-12-4) → benzyl 2-acetamido-2-deoxy-3-O-β-D-galactopyranosyl-β-D-glucopyranoside (80035-19-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 73 percent / mercuric cyanide / acetonitrile / 8 h / Ambient temperature

2: 79 percent / acetic acid (80percent) / 0.5 h / 100 °C

3: 83 percent / sodium methoxide / methanol / Ambient temperature

With sodium methylate; mercury(II) cyanide; acetic acid; In methanol; acetonitrile;

DOI:10.1016/S0008-6215(00)81873-X

upstream raw materials:

benzyl 2-acetamido-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-β-D-glucopyranoside

benzyl 2-acetamido-2-deoxy-4,6-O-isopropylidene-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-β-D-glucopyranoside

benzyl 2-acetamido-2-deoxy-4,6-O-isopropylidene-β-D-glucopyranoside

benzyl 2-acetamido-2-deoxy-β-D-glucopyranoside

Downstream raw materials:

C₁₉H₂₉NO₁₀*ClH

benzyl 2-acetamido-2-deoxy-3-O-<2,3,4,6-tetra-O-(trimethylsilyl)-β-D-galactopyranosyl>-4,6-di-O-(trimethylsilyl)-β-D-glucopyranoside