4-{2-[4-(diphenylamino)phenyl]ethynyl}-N-(2-bromoethyl)-1,8-naphthalimide

Base Information

• Chemical Name: 4-{2-[4-(diphenylamino)phenyl]ethynyl}-N-(2-bromoethyl)-1,8-naphthalimide
• CAS No.: 936614-95-8
• Molecular Formula: C₃₄H₂₃BrN₂O₂
• Molecular Weight: 571.473
• Mol file: 936614-95-8.mol

Synonyms:4-{2-[4-(diphenylamino)phenyl]ethynyl}-N-(2-bromoethyl)-1,8-naphthalimide

Chemical Property of 4-{2-[4-(diphenylamino)phenyl]ethynyl}-N-(2-bromoethyl)-1,8-naphthalimide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-{2-[4-(diphenylamino)phenyl]ethynyl}-N-(2-bromoethyl)-1,8-naphthalimide

There total 3 articles about 4-{2-[4-(diphenylamino)phenyl]ethynyl}-N-(2-bromoethyl)-1,8-naphthalimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

4-{2-[4-(diphenylamino)phenyl]ethynyl}-N-(2-hydroxyethyl)-1,8-naphthalimide → 4-{2-[4-(diphenylamino)phenyl]ethynyl}-N-(2-bromoethyl)-1,8-naphthalimide (936614-95-8)

Guidance literature:

With pyridine; phosphorus tribromide; In chloroform; N,N-dimethyl-formamide; for 3h; Heating;

DOI:10.1016/j.tetlet.2007.02.034

Reference yield:

N-hydroxyethyl-4-bromine-1,8-naphthalimide (52559-37-2) → 4-{2-[4-(diphenylamino)phenyl]ethynyl}-N-(2-bromoethyl)-1,8-naphthalimide (936614-95-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / PPh₃; CuI; triethylamine / Pd(PPh₃)2Cl₂ / dimethylformamide / 12 h / Heating

2: 45 percent / pyridine; PBr₃ / CHCl₃; dimethylformamide / 3 h / Heating

With pyridine; copper(l) iodide; phosphorus tribromide; triethylamine; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride; In chloroform; N,N-dimethyl-formamide;

DOI:10.1016/j.tetlet.2007.02.034

Reference yield:

4-diphenylaminophenylacetylene (205877-26-5) → 4-{2-[4-(diphenylamino)phenyl]ethynyl}-N-(2-bromoethyl)-1,8-naphthalimide (936614-95-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / PPh₃; CuI; triethylamine / Pd(PPh₃)2Cl₂ / dimethylformamide / 12 h / Heating

2: 45 percent / pyridine; PBr₃ / CHCl₃; dimethylformamide / 3 h / Heating

With pyridine; copper(l) iodide; phosphorus tribromide; triethylamine; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride; In chloroform; N,N-dimethyl-formamide;

DOI:10.1016/j.tetlet.2007.02.034

upstream raw materials:

N-hydroxyethyl-4-bromine-1,8-naphthalimide

4-diphenylaminophenylacetylene