2-[2-(4-Cyanophenyl)-ethyl]-1-methyl-5-(4-dimethylaminobenzylamino)-benzimidazole

Base Information

• Chemical Name: 2-[2-(4-Cyanophenyl)-ethyl]-1-methyl-5-(4-dimethylaminobenzylamino)-benzimidazole
• CAS No.: 331766-61-1
• Molecular Formula: C₂₆H₂₇N₅
• Molecular Weight: 409.534

Synonyms:2-[2-(4-Cyanophenyl)-ethyl]-1-methyl-5-(4-dimethylaminobenzylamino)-benzimidazole

Chemical Property of 2-[2-(4-Cyanophenyl)-ethyl]-1-methyl-5-(4-dimethylaminobenzylamino)-benzimidazole

Chemical Property:

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Technology Process of 2-[2-(4-Cyanophenyl)-ethyl]-1-methyl-5-(4-dimethylaminobenzylamino)-benzimidazole

There total 1 articles about 2-[2-(4-Cyanophenyl)-ethyl]-1-methyl-5-(4-dimethylaminobenzylamino)-benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Na[HB(Oac)3] + 4-dimethylamino-benzaldehyde (100-10-7) + 1-methyl-2-[2-(4-cyanophenyl)-ethyl]-5-amino-benzimidazole (256492-47-4) → 2-[2-(4-Cyanophenyl)-ethyl]-1-methyl-5-(4-dimethylaminobenzylamino)-benzimidazole (331766-61-1)

Guidance literature:

With sodium hydroxide; acetic acid; In dichloromethane;

Reference yield: 39.0%

2-[2-(4-Cyanophenyl)-ethyl]-1-methyl-5-(4-dimethylaminobenzylamino)-benzimidazole (331766-61-1) → N-{2-[2-(4-amidinophenyl)-ethyl]-1-methyl-benzimidazol-5-yl}-N-(4-dimethylaminobenzyl)-(benzenesulphonamide)-dihydrochloride

Guidance literature:

upstream raw materials:

4-dimethylamino-benzaldehyde

1-methyl-2-[2-(4-cyanophenyl)-ethyl]-5-amino-benzimidazole

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