C₁₂H₁₇N₃O₅

Base Information

• Chemical Name: C₁₂H₁₇N₃O₅
• CAS No.: 1567843-97-3
• Molecular Formula: C₁₂H₁₇N₃O₅
• Molecular Weight: 283.284
• Mol file: 1567843-97-3.mol

Synonyms:C₁₂H₁₇N₃O₅

Chemical Property of C₁₂H₁₇N₃O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₂H₁₇N₃O₅

There total 7 articles about C₁₂H₁₇N₃O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

ethyl 2-(4-(2-hydroxyethoxy)-3-methoxybenzamido)acetate (1567843-96-2) → C12H17N3O5 (1567843-97-3)

Guidance literature:

With hydrazine hydrate; In ethanol; at 80 ℃; for 15h;

Reference yield:

3-methoxy-4-hydroxybenzoic acid (121-34-6) → C12H17N3O5 (1567843-97-3)

Guidance literature:

Multi-step reaction with 5 steps

1.1: hydrogenchloride / 14 h / 60 °C

2.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere

3.1: potassium hydroxide; methanol / 2 h / 40 °C

4.1: HATU; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.5 h / 20 °C

4.2: 15 h / 20 °C

5.1: hydrazine hydrate / ethanol / 15 h / 80 °C

With hydrogenchloride; methanol; hydrazine hydrate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; HATU; potassium hydroxide; diethylazodicarboxylate; In tetrahydrofuran; ethanol; dichloromethane;

Reference yield:

4-(2-hydroxyethoxyl)-3-methoxybenzoic acid (23294-55-5) → C12H17N3O5 (1567843-97-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: HATU; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.5 h / 20 °C

1.2: 15 h / 20 °C

2.1: hydrazine hydrate / ethanol / 15 h / 80 °C

With hydrazine hydrate; N-ethyl-N,N-diisopropylamine; HATU; In ethanol; dichloromethane;

upstream raw materials:

3-methoxy-4-hydroxybenzoic acid

ethyl vanillate

ethyl 4-(2-hydroxyethoxy)-3-methoxybenzoate

4-(2-hydroxyethoxyl)-3-methoxybenzoic acid

Downstream raw materials:

C₂₂H₂₃N₃O₅S

Refernces