(S)-N-((3-(3,5-difluoro-4-(1-(methoxycarbamoyl)[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)-methyl)-O-methylthiocarbamate

Base Information

Chemical Name:(S)-N-((3-(3,5-difluoro-4-(1-(methoxycarbamoyl)[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)-methyl)-O-methylthiocarbamate
CAS No.:1489240-51-8
Molecular Formula:C₁₈H₂₄F₂N₆O₅S
Molecular Weight:474.489
Hs Code.:

Synonyms:(S)-N-((3-(3,5-difluoro-4-(1-(methoxycarbamoyl)[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)-methyl)-O-methylthiocarbamate

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Chemical Property of (S)-N-((3-(3,5-difluoro-4-(1-(methoxycarbamoyl)[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)-methyl)-O-methylthiocarbamate

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Technology Process of (S)-N-((3-(3,5-difluoro-4-(1-(methoxycarbamoyl)[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)-methyl)-O-methylthiocarbamate

There total 2 articles about (S)-N-((3-(3,5-difluoro-4-(1-(methoxycarbamoyl)[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)-methyl)-O-methylthiocarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₃H₃₂F₂N₆O₇S

: 1489240-51-8
(S)-N-((3-(3,5-difluoro-4-(1-(methoxycarbamoyl)[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)-methyl)-O-methylthiocarbamate

Guidance literature:: With hydrogenchloride; water; In 1,4-dioxane; at 20 ℃; for 2h;
DOI:10.1016/j.ejmech.2013.08.002

Reference yield:

: 952151-87-0
O-methyl (S)-N-(3-(4-(1-(tert-butoxycarbonyl)[1,2,5]triazepan-5-yl)-3,5-difluorophenyl)-2-oxooxazolidin-5-yl)methylthiocarbamate

: 1489240-51-8
(S)-N-((3-(3,5-difluoro-4-(1-(methoxycarbamoyl)[1,2,5]triazepan-5-yl)phenyl)-2-oxo-5-oxazolidinyl)-methyl)-O-methylthiocarbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / tetrahydrofuran / 0.17 h / 0 °C

1.2: 24 h / 20 °C

2.1: hydrogenchloride; water / 1,4-dioxane / 2 h / 20 °C

With hydrogenchloride; water; triethylamine; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1016/j.ejmech.2013.08.002