1,3-bis(3,5-di-tert-butyl-2-hydroxybenzyl)imidazolium chloride

Base Information

• Chemical Name: 1,3-bis(3,5-di-tert-butyl-2-hydroxybenzyl)imidazolium chloride
• CAS No.: 1187398-72-6
• Molecular Formula: C₃₃H₄₉N₂O₂*Cl
• Molecular Weight: 541.217
• Mol file: 1187398-72-6.mol

Synonyms:1,3-bis(3,5-di-tert-butyl-2-hydroxybenzyl)imidazolium chloride

Chemical Property of 1,3-bis(3,5-di-tert-butyl-2-hydroxybenzyl)imidazolium chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-bis(3,5-di-tert-butyl-2-hydroxybenzyl)imidazolium chloride

There total 2 articles about 1,3-bis(3,5-di-tert-butyl-2-hydroxybenzyl)imidazolium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1H-imidazole (288-32-4) + 2,4-di-tertbutyl-6-chloromethylphenol (10193-84-7) → 1,3-bis(3,5-di-tert-butyl-2-hydroxybenzyl)imidazolium chloride (1187398-72-6)

Guidance literature:

With sodium hydrogencarbonate; In tetrahydrofuran; for 1.5h; Schlenk technique; Reflux;

Reference yield:

3,5-di-tert-butyl-2-hydroxybenzaldehyde (37942-07-7) → 1,3-bis(3,5-di-tert-butyl-2-hydroxybenzyl)imidazolium chloride (1187398-72-6)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium tetrahydroborate / ethanol / 0.5 h / 20 °C / Inert atmosphere

2: thionyl chloride / toluene / 0.75 h / 20 °C / Schlenk technique

3: sodium hydrogencarbonate / tetrahydrofuran / 1.5 h / Schlenk technique; Reflux

With sodium tetrahydroborate; thionyl chloride; sodium hydrogencarbonate; In tetrahydrofuran; ethanol; toluene;

Reference yield: 90.0%

1,3-bis(3,5-di-tert-butyl-2-hydroxybenzyl)imidazolium chloride (1187398-72-6) → C33H49N2O2(1+)*Cl4Fe(1-)

Guidance literature:

With iron(III) chloride; In tetrahydrofuran; at 20 ℃; for 3h;

DOI:10.1039/c2dt30931a

upstream raw materials:

1H-imidazole

2,4-di-tertbutyl-6-chloromethylphenol

3,5-di-tert-butyl-2-hydroxybenzaldehyde

Refernces