1-Methyl-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-2-(4-acetoxy-benzyl)-benzene

Base Information

• Chemical Name: 1-Methyl-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-2-(4-acetoxy-benzyl)-benzene
• CAS No.: 912917-86-3
• Molecular Formula: C₃₀H₃₄O₁₁
• Molecular Weight: 570.593
• Mol file: 912917-86-3.mol

Synonyms:1-Methyl-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-2-(4-acetoxy-benzyl)-benzene

Chemical Property of 1-Methyl-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-2-(4-acetoxy-benzyl)-benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Methyl-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-2-(4-acetoxy-benzyl)-benzene

There total 2 articles about 1-Methyl-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-2-(4-acetoxy-benzyl)-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

2-(4-hydroxybenzyl)-4-(1-methoxy-β-D-glucopyranos-1-yl)-1-methyl-benzene (1022080-14-3) + acetic anhydride (108-24-7) → 1-Methyl-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-2-(4-acetoxy-benzyl)-benzene (912917-86-3)

Guidance literature:

2-(4-hydroxybenzyl)-4-(1-methoxy-β-D-glucopyranos-1-yl)-1-methyl-benzene; With triethylsilane; boron trifluoride diethyl etherate; In dichloromethane; acetonitrile; at -20 - 0 ℃; for 0.5h;

With potassium hydroxide; In dichloromethane; water; acetonitrile; at 20 ℃; for 0.25h;

acetic anhydride; With pyridine; hydrogenchloride; dmap; more than 3 stages;

Reference yield:

→ 1-Methyl-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-2-(4-acetoxy-benzyl)-benzene (912917-86-3)

Guidance literature:

Reference yield: 100.0%

1-Methyl-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-2-(4-acetoxy-benzyl)-benzene (912917-86-3) → (2S,3R,4R,5S,6R)-2-(3-(4-hydroxybenzyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (333360-66-0)

Guidance literature:

1-Methyl-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-2-(4-acetoxy-benzyl)-benzene; With potassium hydroxide; water; In tetrahydrofuran; methanol; at 20 ℃; for 0.5h;

With hydrogenchloride; In tetrahydrofuran; methanol; water;

upstream raw materials:

2-(4-hydroxybenzyl)-4-(1-methoxy-β-D-glucopyranos-1-yl)-1-methyl-benzene

acetic anhydride

Downstream raw materials:

(2S,3R,4R,5S,6R)-2-(3-(4-hydroxybenzyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol