S,S'-bis-benzyl-N,N'-bis-benzyloxycarbonyl ethylene bis-L-β-homocysteine

Base Information

Chemical Name:S,S'-bis-benzyl-N,N'-bis-benzyloxycarbonyl ethylene bis-L-β-homocysteine
CAS No.:246039-26-9
Molecular Formula:C₄₀H₄₄N₂O₈S₂
Molecular Weight:744.93
Hs Code.:

Synonyms:S,S'-bis-benzyl-N,N'-bis-benzyloxycarbonyl ethylene bis-L-β-homocysteine

Suppliers and Price of S,S'-bis-benzyl-N,N'-bis-benzyloxycarbonyl ethylene bis-L-β-homocysteine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of S,S'-bis-benzyl-N,N'-bis-benzyloxycarbonyl ethylene bis-L-β-homocysteine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of S,S'-bis-benzyl-N,N'-bis-benzyloxycarbonyl ethylene bis-L-β-homocysteine

There total 6 articles about S,S'-bis-benzyl-N,N'-bis-benzyloxycarbonyl ethylene bis-L-β-homocysteine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 246039-25-8
S,S'-bis-benzyl-N,N'-bis-benzyloxycarbonyl ethylene bis-L-β-homocysteine dimethylester

: 246039-26-9
S,S'-bis-benzyl-N,N'-bis-benzyloxycarbonyl ethylene bis-L-β-homocysteine

Guidance literature:: With sodium hydroxide; In methanol; water; at 50 ℃; for 12h;
DOI:10.1002/(SICI)1099-1344(199907)42:7<683::AID-JLCR230>3.0.CO;2-0

Reference yield:

: 14344-48-0
N,N'-ethylenebis(L-cysteine)

: 246039-26-9
S,S'-bis-benzyl-N,N'-bis-benzyloxycarbonyl ethylene bis-L-β-homocysteine

Guidance literature:: Multi-step reaction with 5 steps

1.1: Na / liquid ammonia / 0.5 h

2.1: 87 percent / Na₂CO₃; NaOH / H₂O; dioxane / 2 h / pH 10

3.1: isobutyl chloroformate; N-methyl morpholine / tetrahydrofuran / 1 h / -5 °C

3.2: 84 percent / tetrahydrofuran; diethyl ether / 4 h / 0 °C

4.1: 10 percent / silver benzoate; Et₃N / 0.33 h

5.1: 61 percent / NaOH / methanol; H₂O / 12 h / 50 °C

With 4-methyl-morpholine; sodium hydroxide; silver benzoate; sodium; sodium carbonate; triethylamine; isobutyl chloroformate; In tetrahydrofuran; 1,4-dioxane; methanol; ammonia; water; 1.1: Alkylation / 2.1: Substitution / 3.1: Substitution / 3.2: Substitution / 4.1: Rearrangement / 5.1: Hydrolysis;
DOI:10.1002/(SICI)1099-1344(199907)42:7<683::AID-JLCR230>3.0.CO;2-0

Reference yield:

: 14344-59-3
S,S'-bis-benzyl ethylene-bis-L-cysteine

: 246039-26-9
S,S'-bis-benzyl-N,N'-bis-benzyloxycarbonyl ethylene bis-L-β-homocysteine

Guidance literature:: Multi-step reaction with 4 steps

1.1: 87 percent / Na₂CO₃; NaOH / H₂O; dioxane / 2 h / pH 10

2.1: isobutyl chloroformate; N-methyl morpholine / tetrahydrofuran / 1 h / -5 °C

2.2: 84 percent / tetrahydrofuran; diethyl ether / 4 h / 0 °C

3.1: 10 percent / silver benzoate; Et₃N / 0.33 h

4.1: 61 percent / NaOH / methanol; H₂O / 12 h / 50 °C

With 4-methyl-morpholine; sodium hydroxide; silver benzoate; sodium carbonate; triethylamine; isobutyl chloroformate; In tetrahydrofuran; 1,4-dioxane; methanol; water; 1.1: Substitution / 2.1: Substitution / 2.2: Substitution / 3.1: Rearrangement / 4.1: Hydrolysis;
DOI:10.1002/(SICI)1099-1344(199907)42:7<683::AID-JLCR230>3.0.CO;2-0