(R)-2-[(1S,2R)-1-hydroxy-2-(methoxymethoxy)-2-phenylethyl]cyclopentanone

Base Information

Chemical Name:(R)-2-[(1S,2R)-1-hydroxy-2-(methoxymethoxy)-2-phenylethyl]cyclopentanone
CAS No.:1632036-73-7
Molecular Formula:C₁₅H₂₀O₄
Molecular Weight:264.321
Hs Code.:

Synonyms:(R)-2-[(1S,2R)-1-hydroxy-2-(methoxymethoxy)-2-phenylethyl]cyclopentanone

Suppliers and Price of (R)-2-[(1S,2R)-1-hydroxy-2-(methoxymethoxy)-2-phenylethyl]cyclopentanone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2-[(1S,2R)-1-hydroxy-2-(methoxymethoxy)-2-phenylethyl]cyclopentanone

Chemical Property:

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Technology Process of (R)-2-[(1S,2R)-1-hydroxy-2-(methoxymethoxy)-2-phenylethyl]cyclopentanone

There total 2 articles about (R)-2-[(1S,2R)-1-hydroxy-2-(methoxymethoxy)-2-phenylethyl]cyclopentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 107536-09-4,120113-93-1,121842-15-7,121842-14-6
(2R)-2-methoxymethoxy-3-phenylacetaldehyde

: 120-92-3
cyclopentanone

: 1632036-75-9
(R)-2-[(1R,2R)-1-hydroxy-2-(methoxymethoxy)-2-phenylethyl]cyclopentanone

: 1632036-73-7
(R)-2-[(1S,2R)-1-hydroxy-2-(methoxymethoxy)-2-phenylethyl]cyclopentanone

Guidance literature:: With L-proline; at 20 ℃; for 12h; diastereoselective reaction;
DOI:10.1055/s-0033-1341107

Reference yield:

: 269402-51-9
(R)-2-methyloxymethoxy-2-phenyl-1-ethanol

: 1632036-75-9
(R)-2-[(1R,2R)-1-hydroxy-2-(methoxymethoxy)-2-phenylethyl]cyclopentanone

: 1632036-73-7
(R)-2-[(1S,2R)-1-hydroxy-2-(methoxymethoxy)-2-phenylethyl]cyclopentanone

Guidance literature:: Multi-step reaction with 2 steps

1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / dimethyl sulfoxide; ethyl acetate / 2 h / 20 °C / Reflux

2: L-proline / 12 h / 20 °C

With L-proline; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In dimethyl sulfoxide; ethyl acetate; 2: |Aldol Condensation;
DOI:10.1055/s-0033-1341107