Technology Process of 4-benzyl-5-bromo-2-hydroxypyridine
There total 6 articles about 4-benzyl-5-bromo-2-hydroxypyridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen bromide;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: methanol
2: sodium borohydrid / methanol; water
3: pyridine; acetic anhydride / hexane; water; ethyl acetate
4: palladium-carbon / methanol
5: potassium hydroxide; potassium bromide; tetraethylammonium chloride; bromine; sodium sulfite / hexane; water; ethyl acetate
6: hydrogen bromide
With
pyridine; potassium hydroxide; potassium bromide; sodium borohydrid; tetraethylammonium chloride; hydrogen bromide; bromine; acetic anhydride; sodium sulfite;
palladium-carbon;
In
methanol; hexane; water; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium borohydrid / methanol; water
2: pyridine; acetic anhydride / hexane; water; ethyl acetate
3: palladium-carbon / methanol
4: potassium hydroxide; potassium bromide; tetraethylammonium chloride; bromine; sodium sulfite / hexane; water; ethyl acetate
5: hydrogen bromide
With
pyridine; potassium hydroxide; potassium bromide; sodium borohydrid; tetraethylammonium chloride; hydrogen bromide; bromine; acetic anhydride; sodium sulfite;
palladium-carbon;
In
methanol; hexane; water; ethyl acetate;
