3-(2-(4-Hydroxy-4-phenyl-1-piperidinyl)ethyl)-2-(4-nitrophenyl)-4-thiazolidinone

Base Information

Chemical Name:3-(2-(4-Hydroxy-4-phenyl-1-piperidinyl)ethyl)-2-(4-nitrophenyl)-4-thiazolidinone
CAS No.:182188-88-1
Molecular Formula:C₂₂H₂₅N₃O₄S
Molecular Weight:427.524
Hs Code.:
DSSTox Substance ID:DTXSID50939533
Nikkaji Number:J861.523C
Mol file:182188-88-1.mol

Synonyms:182188-88-1;3-(2-(4-Hydroxy-4-phenyl-1-piperidinyl)ethyl)-2-(4-nitrophenyl)-4-thiazolidinone;3-[2-(4-hydroxy-4-phenylpiperidin-1-yl)ethyl]-2-(4-nitrophenyl)-1,3-thiazolidin-4-one;4-Thiazolidinone, 3-(2-(4-hydroxy-4-phenyl-1-piperidinyl)ethyl)-2-(4-nitrophenyl)-;3-[2-(4-hydroxy-4-phenyl-1-piperidyl)ethyl]-2-(4-nitrophenyl)thiazolid in-4-one;DTXSID50939533;XDEWPWGNMSOAKL-UHFFFAOYSA-N;LS-151787;2-(4-Nitrophenyl)-3-[2-(4-hydroxy-4-phenylpiperidino)ethyl]thiazolidin-4-one

Suppliers and Price of 3-(2-(4-Hydroxy-4-phenyl-1-piperidinyl)ethyl)-2-(4-nitrophenyl)-4-thiazolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-(2-(4-Hydroxy-4-phenyl-1-piperidinyl)ethyl)-2-(4-nitrophenyl)-4-thiazolidinone

Chemical Property:

Vapor Pressure:1.98E-19mmHg at 25°C
Boiling Point:680.1°Cat760mmHg
Flash Point:365.1°C
PSA：114.90000
Density:1.325g/cm³
LogP:3.55140
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:427.15657746
Heavy Atom Count:30
Complexity:606

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1(C2=CC=CC=C2)O)CCN3C(SCC3=O)C4=CC=C(C=C4)[N+](=O)[O-]

Technology Process of 3-(2-(4-Hydroxy-4-phenyl-1-piperidinyl)ethyl)-2-(4-nitrophenyl)-4-thiazolidinone

There total 4 articles about 3-(2-(4-Hydroxy-4-phenyl-1-piperidinyl)ethyl)-2-(4-nitrophenyl)-4-thiazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 40807-61-2
4-hydroxy-4-phenylpiperidin

: 182188-88-1
3-[2-(4-Hydroxy-4-phenyl-piperidin-1-yl)-ethyl]-2-(4-nitro-phenyl)-thiazolidin-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: 54 percent / Et₃N / acetonitrile / 48 h / Ambient temperature

2: 80 percent / N₂H₄*H₂O / methanol / 4 h / Heating

3: benzene / Heating

4: benzene / Heating

With hydrazine hydrate; triethylamine; In methanol; acetonitrile; benzene;

Reference yield:

: 25557-40-8
2-[2-(4-Hydroxy-4-phenyl-piperidin-1-yl)-ethyl]-isoindole-1,3-dione

: 182188-88-1
3-[2-(4-Hydroxy-4-phenyl-piperidin-1-yl)-ethyl]-2-(4-nitro-phenyl)-thiazolidin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / N₂H₄*H₂O / methanol / 4 h / Heating

2: benzene / Heating

3: benzene / Heating

With hydrazine hydrate; In methanol; benzene;