(2E,5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hepta-2,5-dienal

Base Information

Chemical Name:(2E,5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hepta-2,5-dienal
CAS No.:62410-84-8
Molecular Formula:C₂₀H₃₂O₄
Molecular Weight:336.472
Hs Code.:
DSSTox Substance ID:DTXSID801347865
Mol file:62410-84-8.mol

Synonyms:PGF2-alpha 1,11-lactone;BRN 5596377;Prostaglandin F2-alpha 1,11-lactone;(2E,5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hepta-2,5-dienal;Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, iota-lactone, (5Z,9-alpha,11-alpha,13E,15S)-;DTXSID801347865;LS-125836;9ALPHA,11ALPHA,15S-TRIHYDROXY-PROSTA-5Z,13E-DIEN-1-OICACID,1,11-LACTONE

Suppliers and Price of (2E,5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hepta-2,5-dienal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
Prostaglandin F2α 1,11-lactone ≥98%
5mg
$ 341.00

Cayman Chemical
Prostaglandin F2α 1,11-lactone ≥98%
1mg
$ 77.00

Cayman Chemical
Prostaglandin F2α 1,11-lactone ≥98%
10mg
$ 605.00

American Custom Chemicals Corporation
9-ALPHA-11ALPHA-15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID-1,11-LACTONE 95.00%
5MG
$ 496.33

AK Scientific
9alpha,11alpha,15S-Trihydroxy-prosta-5Z,13E-dien-1-oicacid,1,11-lactone
10mg
$ 856.00

Total 4 raw suppliers

Chemical Property of (2E,5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hepta-2,5-dienal

Chemical Property:

Vapor Pressure:4.96E-12mmHg at 25°C
Boiling Point:498.6 °C at 760 mmHg
Flash Point:269.4 °C
PSA：66.76000
Density:1.108 g/cm3
LogP:3.52280
XLogP3:2.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:11
Exact Mass:336.23005950
Heavy Atom Count:24
Complexity:427

Purity/Quality:

99% ^*data from raw suppliers

Prostaglandin F2α 1,11-lactone ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC(C=CC1C(CC(C1CC=CCC=CC=O)O)O)O
Isomeric SMILES:CCCCC[C@@H](/C=C/[C@H]1[C@@H](C[C@@H]([C@@H]1C/C=C\C/C=C/C=O)O)O)O

Technology Process of (2E,5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hepta-2,5-dienal

There total 5 articles about (2E,5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hepta-2,5-dienal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 62410-87-1
(Z)-(1R,10R,11S,13R)-11-Triphenylsilanyloxy-13-((E)-(S)-3-triphenylsilanyloxy-oct-1-enyl)-2-oxa-bicyclo[8.2.1]tridec-7-en-3-one

: 62410-84-8
prostaglandin F_2α 1,11-lactone

Guidance literature:: With phosphoric acid; In tetrahydrofuran; at 45 ℃; for 2h;
DOI:10.1021/jm00362a001

Reference yield:

: 41598-07-6
prostaglandin D₂

: 62410-84-8
prostaglandin F_2α 1,11-lactone

Guidance literature:: Multi-step reaction with 5 steps

1: 87 percent / pyridine / 6 h / 25 °C

2: 71 percent / NaBH₄ / methanol / 0.25 h / 0 °C

3: Ph₃P / xylene / 10 h / 25 °C

4: xylene / 24 h / Heating

5: 71 percent / aq. H₃PO₄ / tetrahydrofuran / 2 h / 45 °C

With pyridine; sodium tetrahydroborate; phosphoric acid; triphenylphosphine; In tetrahydrofuran; methanol; xylene;
DOI:10.1021/jm00362a001

Reference yield:

: 62410-85-9
PGD₂ 9,15-bis(triphenylsilyl ether)

: 62410-84-8
prostaglandin F_2α 1,11-lactone

Guidance literature:: Multi-step reaction with 4 steps

1: 71 percent / NaBH₄ / methanol / 0.25 h / 0 °C

2: Ph₃P / xylene / 10 h / 25 °C

3: xylene / 24 h / Heating

4: 71 percent / aq. H₃PO₄ / tetrahydrofuran / 2 h / 45 °C

With sodium tetrahydroborate; phosphoric acid; triphenylphosphine; In tetrahydrofuran; methanol; xylene;
DOI:10.1021/jm00362a001