INSULIN LISPRO (5.97 MG)

Base Information

• Chemical Name: INSULIN LISPRO (5.97 MG)
• CAS No.: 133107-64-9
• Molecular Formula: C257H383 N65 O77 S6
• Molecular Weight: 5807.57022
• Hs Code.: 2937190000
• Mol file: 133107-64-9.mol

Synonyms:Insulin(ox),8A-L-threonine-10A-L-isoleucine-28B-L-lysine-29B-L-proline-30B-L-threonine-;3,4,44,45,90,91-Hexathia-8,11,14,17,20,23,26,29,32,35,38,41,48,51,54,57,60,63,66,69,72,75,78,81,84,86-hexacosaazabicyclo[72.11.7]dononacontane,cyclic peptide deriv.; 28B-L-Lysine-29B-L-prolineinsulin (human); 3: PN:WO2004005342 PAGE: 46 claimed protein; Humalog; Humalog Lispro; Humalog R;Insulin lispro; LY 275585; Lispro; [Lys(B28), Pro(B29)]-Human insulin

Chemical Property of INSULIN LISPRO (5.97 MG)

Chemical Property:

• PSA: 2450.87000
• LogP: 5.20780
• Solubility.: Practically insoluble in water and in ethanol (96 per cent). It dissolves in dilute mineral acids and with decomposition in dilute solutions of alkali hydroxides.

Purity/Quality:

97% ^*data from raw suppliers

Insulin lispro ^*data from reagent suppliers

Safty Information:

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Useful:

• Description: Humalog was launched in 1996 in Australia, Denmark, Germany, Russia, S. Africa, Spain, Sweden, Switzerland, Canada, Czech Republic, Lithuania, the UK and the US as a fast-acting human insulin analog. It was prepared by recombinant DNA technology using a non-disease producing laboratory strain of E. coh containing the gene for insulin lispro precursor protein and purified as a zinc complex. Conceptually designed from insulin-like growth factor I (IGF-I) the amino acid residues 28 and 29 of B chain have been inverted. This modification reduces the propensity to form dimers and the dimers to form hexamers. Thus this form of insulin has an increased rate of absorption since dissociation of the hexamer to monomer is the rate limiting step. The rapid absorption and short duration of action results in a significant advantage in controlling blood glucose levels after meals compared to normal insulin.
• Uses: Antidiabetic.

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