C₂₀H₂₃NO₃

Base Information

• Chemical Name: C₂₀H₂₃NO₃
• CAS No.: 155227-25-1
• Molecular Formula: C₂₀H₂₃NO₃
• Molecular Weight: 325.408
• Mol file: 155227-25-1.mol

Synonyms:C₂₀H₂₃NO₃

Chemical Property of C₂₀H₂₃NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₃NO₃

There total 8 articles about C₂₀H₂₃NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

((1R,2R,4S)-3,3-dimethylbicyclo[2.2.1]heptan-2-yl)methanol (81601-68-5) → C20H23NO3 (155227-25-1)

Guidance literature:

Multi-step reaction with 4 steps

1: Et₃N / toluene; diethyl ether / 0 °C

2: sodium azide, Bu₄NBr / CH₂Cl₂; H₂O / 25 °C

3: 70 percent / tetrachloroethene

4: n-BuLi

With n-butyllithium; sodium azide; tetrabutylammomium bromide; triethylamine; In 1,1,2,2-tetrachloroethylene; diethyl ether; dichloromethane; water; toluene;

DOI:10.1016/0040-4039(94)85088-7

Reference yield:

C11H17ClO2 → C20H23NO3 (155227-25-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium azide, Bu₄NBr / CH₂Cl₂; H₂O / 25 °C

2: 70 percent / tetrachloroethene

3: n-BuLi

With n-butyllithium; sodium azide; tetrabutylammomium bromide; In 1,1,2,2-tetrachloroethylene; dichloromethane; water;

DOI:10.1016/0040-4039(94)85088-7

Reference yield:

C11H17N3O2 (155325-62-5) → C20H23NO3 (155227-25-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / tetrachloroethene

2: n-BuLi

With n-butyllithium; In 1,1,2,2-tetrachloroethylene;

DOI:10.1016/0040-4039(94)85088-7

upstream raw materials:

Cinnamoyl chloride

(5S)-4-aza-2-oxa-6,6-dimethyl-7,10-methylene-5-spiro<4.5>decan-3-one

camphene

((1R,2R,4S)-3,3-dimethylbicyclo[2.2.1]heptan-2-yl)methanol

Downstream raw materials:

phenylmethyl (3R,4R,5S,6S)-5-phenylbicyclo<2.2.1>heptene-4-carboxylate

(S)-3-phenylvaleric acid

C₂₅H₂₉NO₃

Refernces

• 1、 Banks, Malcolm R.,Cadogan, J. I. G.,Gosney, Ian,Grant, Keith J.,Hodgson, Philip K. G.,Thorburn, Paul. "SYNTHESIS OF ENANTIOMERICALLY PURE (5S)-4-AZA-2-OXA-6,6-DIMETHYL-7,10-METHYLENE-5-SPIRODECAN-3-ONE, A NOVEL CHIRAL OXAZOLIDIN-2-ONE FROM (-)-CAMPHENE FOR USE AS A RECYCLABLE CHIRAL AUXILIARY IN ASYMMETRIC TRANSFORMATIONS". . p. 199 - 206. Retrieved 2007/10/02.