[Trimethylsilanyloxy-(1-trimethylsilanyloxy-butylsulfanyl)-methyl]-cyclohexane

Base Information

• Chemical Name: [Trimethylsilanyloxy-(1-trimethylsilanyloxy-butylsulfanyl)-methyl]-cyclohexane
• CAS No.: 78606-86-7
• Molecular Formula: C₁₇H₃₈O₂SSi₂
• Molecular Weight: 362.725
• Mol file: 78606-86-7.mol

Synonyms:[Trimethylsilanyloxy-(1-trimethylsilanyloxy-butylsulfanyl)-methyl]-cyclohexane

Chemical Property of [Trimethylsilanyloxy-(1-trimethylsilanyloxy-butylsulfanyl)-methyl]-cyclohexane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [Trimethylsilanyloxy-(1-trimethylsilanyloxy-butylsulfanyl)-methyl]-cyclohexane

There total 2 articles about [Trimethylsilanyloxy-(1-trimethylsilanyloxy-butylsulfanyl)-methyl]-cyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

R=CH3CH2CH2 (78606-87-8) + cyclohexanecarbaldehyde (2043-61-0) → [Trimethylsilanyloxy-(1-trimethylsilanyloxy-butylsulfanyl)-methyl]-cyclohexane (78606-86-7)

Guidance literature:

With (K-18-crown-6 ether) cyanide; at 40 ℃; for 48h; Heating;

DOI:10.1016/S0040-4039(01)90244-8

Reference yield:

R=CH3CH2CH2 (78371-35-4) → [Trimethylsilanyloxy-(1-trimethylsilanyloxy-butylsulfanyl)-methyl]-cyclohexane (78606-86-7)

Guidance literature:

Multi-step reaction with 2 steps

1: triethyamine / diethyl ether / 40 °C

2: 76 percent / potassium cyanide-18-crown-6-ether complex / 48 h / 40 °C / Heating

With (K-18-crown-6 ether) cyanide; triethylamine; In diethyl ether;

DOI:10.1016/S0040-4039(01)90244-8

Reference yield:

[Trimethylsilanyloxy-(1-trimethylsilanyloxy-butylsulfanyl)-methyl]-cyclohexane (78606-86-7) → [((E)-But-1-enyl)sulfanylmethylene]-cyclohexane (78606-92-5)

Guidance literature:

With trimethylsilyl iodide; triethylamine; Yield given. Multistep reaction; 1.) dichloromethane, -78 deg C, 20 min 2.) 0 deg C, overnight;

DOI:10.1016/S0040-4039(01)90244-8

upstream raw materials:

R=CH₃CH₂CH₂

cyclohexanecarbaldehyde

R=CH₃CH₂CH₂

Downstream raw materials:

[((E)-But-1-enyl)sulfanylmethylene]-cyclohexane