(S)-methyl 2-(4-((5-((1-(3-cyclopropylphenyl)ethyl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)phenoxy)acetate

Base Information

Chemical Name:(S)-methyl 2-(4-((5-((1-(3-cyclopropylphenyl)ethyl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)phenoxy)acetate
CAS No.:1415323-25-9
Molecular Formula:C₃₂H₃₄N₂O₄
Molecular Weight:510.633
Hs Code.:

Synonyms:(S)-methyl 2-(4-((5-((1-(3-cyclopropylphenyl)ethyl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)phenoxy)acetate

Suppliers and Price of (S)-methyl 2-(4-((5-((1-(3-cyclopropylphenyl)ethyl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)phenoxy)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-methyl 2-(4-((5-((1-(3-cyclopropylphenyl)ethyl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)phenoxy)acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-methyl 2-(4-((5-((1-(3-cyclopropylphenyl)ethyl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)phenoxy)acetate

There total 5 articles about (S)-methyl 2-(4-((5-((1-(3-cyclopropylphenyl)ethyl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)phenoxy)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1415325-11-9
(S)-1-(3-cyclopropylphenyl)ethanamine hydrochloride

: 1415323-24-8
1-(4-(2-methoxy-2-oxoethoxy)benzyl)-2,3-dimethyl-1H-indole-5-carboxylic acid

: 1415323-25-9
(S)-methyl 2-(4-((5-((1-(3-cyclopropylphenyl)ethyl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)phenoxy)acetate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane; at 20 ℃; for 0.5h;

Reference yield:

: 106-44-5
p-cresol

: 1415323-25-9
(S)-methyl 2-(4-((5-((1-(3-cyclopropylphenyl)ethyl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)phenoxy)acetate

Guidance literature:: Multi-step reaction with 5 steps

1: caesium carbonate / N,N-dimethyl-formamide / 3 h / 20 °C

2: dibenzoyl peroxide; N-Bromosuccinimide / tetrachloromethane / Reflux

3: sodium hydride / N,N-dimethyl-formamide; mineral oil / Inert atmosphere

4: morpholine / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran / 1.5 h / Inert atmosphere

5: N-ethyl-N,N-diisopropylamine; HATU / dichloromethane / 0.5 h / 20 °C

With morpholine; N-Bromosuccinimide; sodium hydride; caesium carbonate; N-ethyl-N,N-diisopropylamine; HATU; dibenzoyl peroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; tetrachloromethane; dichloromethane; N,N-dimethyl-formamide; mineral oil;

Reference yield:

: 104508-23-8
methyl 2-(4-(bromomethyl)phenoxy)acetate

: 1415323-25-9
(S)-methyl 2-(4-((5-((1-(3-cyclopropylphenyl)ethyl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)phenoxy)acetate

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydride / N,N-dimethyl-formamide; mineral oil / Inert atmosphere

2: morpholine / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran / 1.5 h / Inert atmosphere

3: N-ethyl-N,N-diisopropylamine; HATU / dichloromethane / 0.5 h / 20 °C

With morpholine; sodium hydride; N-ethyl-N,N-diisopropylamine; HATU; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; mineral oil;