1-Benzoyl-3-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-thiourea

Base Information

Chemical Name:1-Benzoyl-3-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-thiourea
CAS No.:121378-20-9
Molecular Formula:C₂₄H₂₂N₄O₂S
Molecular Weight:430.53
Hs Code.:

Synonyms:1-Benzoyl-3-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-thiourea

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Chemical Property of 1-Benzoyl-3-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-thiourea

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Technology Process of 1-Benzoyl-3-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-thiourea

There total 1 articles about 1-Benzoyl-3-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 118489-98-8
1-(2-Amino-ethyl)-2-phenyl-2,3-dihydro-1H-quinazolin-4-one

: 532-55-8
Benzoyl isothiocyanate

: 121378-20-9
1-Benzoyl-3-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-thiourea

Guidance literature:: In dichloromethane; for 1h; Heating;
DOI:10.1002/ardp.19893220212

Reference yield: 90.0%

: 121378-20-9
1-Benzoyl-3-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-thiourea

: 121378-26-5
[2-(4-Oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-thiourea

Guidance literature:: With potassium carbonate; In methanol; water; for 0.5h; Heating;
DOI:10.1002/ardp.19893220212

Reference yield:

: 121378-20-9
1-Benzoyl-3-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-thiourea

: 2-Methyl-1-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-isothiourea; hydriodide

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / K₂CO₃ / methanol; H₂O / 0.5 h / Heating

2: ethanol / Ambient temperature

With potassium carbonate; In methanol; ethanol; water;
DOI:10.1002/ardp.19893220212