CID 14015196

Base Information

Chemical Name:CID 14015196
CAS No.:119477-85-9
Molecular Formula:C₂₂H₃₅NO₃
Molecular Weight:361.525
Hs Code.:
European Community (EC) Number:634-249-7
Mol file:119477-85-9.mol

Synonyms:6-(6-(3-hydroxy-1,5-undecadien-1-yl)-2-pyridinyl)-1,5-hexanediol;U 75302;U-75302;U75302

Suppliers and Price of CID 14015196

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
U-75302
1mg
$ 630.00

Cayman Chemical
U-75302 ≥98%
500μg
$ 578.00

Cayman Chemical
U-75302 ≥98%
100μg
$ 129.00

Cayman Chemical
U-75302 ≥98%
50μg
$ 68.00

Cayman Chemical
U-75302
1000μg
$ 952.00

American Custom Chemicals Corporation
U-75302 95.00%
1MG
$ 1856.40

Total 9 raw suppliers

Chemical Property of CID 14015196

Chemical Property:

Appearance/Colour:light yellow oil
Vapor Pressure:1.05E-13mmHg at 25°C
Boiling Point:567.2 °C at 760 mmHg
Flash Point:296.8 °C
PSA：73.58000
Density:1.058 g/cm³
LogP:4.04830
Storage Temp.:−20°C
Solubility.:DMSO: 10 mg/mL
XLogP3:4.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:14
Exact Mass:361.26169398
Heavy Atom Count:26
Complexity:384

Purity/Quality:

99% ^*data from raw suppliers

U-75302 ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC=CCC(C=CC1=CC=CC(=N1)CC(CCCCO)O)O
Isomeric SMILES:CCCCC/C=C/CC(/C=C/C1=CC=CC(=N1)CC(CCCCO)O)O
Description U-75302 is an LTB4 receptor antagonist with a Ki of 159 nM on guinea pig lung membranes. This activity is specific for the BLT1 receptor; U-75302 does not antagonize the binding of [3H]-LTB4 to the human BLT2 receptor.
Uses U-75302 is a selective leukotriene B4 antagonist.

Technology Process of CID 14015196

There total 15 articles about CID 14015196 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 116897-21-3,117160-70-0,118824-73-0
6-[6-((Z)-3-Hydroxy-undec-5-en-1-ynyl)-pyridin-2-ylmethyl]-tetrahydro-pyran-2-one

: 116897-14-4,116897-22-4,118789-86-9,119477-85-9,127760-28-5,127760-29-6,127760-30-9
U-75302

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene; at 23 ℃;
DOI:10.1016/S0040-4039(00)80037-4

Reference yield: 83.0%

: 127705-36-6
(S)-6-[6-((Z)-(R)-3-Hydroxy-undec-5-en-1-ynyl)-pyridin-2-yl]-hexane-1,5-diol

: 119477-85-9
U 75302

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride;
DOI:10.1016/S0040-4039(01)93452-5

Reference yield:

: 34160-40-2
6-bromo-2-pyridinecarbaldehyde

: 116897-14-4,116897-22-4,118789-86-9,119477-85-9,127760-28-5,127760-29-6,127760-30-9
U-75302

Guidance literature:: Multi-step reaction with 4 steps

1: LiN(TMS)2 / tetrahydrofuran / Ambient temperature

2: 71 percent / n-Bu₃SnH / AIBN / toluene / 75 °C

3: 99 percent / acetylene, (bis)triphenyl-phosphinepalladium-dichloride / Pd-Cu / triethylamine / 4 h / 50 °C

4: 92 percent / sodium (bis)-2-methoxyethoxy aluminium hydride (Red-Al) / toluene / 23 °C

With bis-triphenylphosphine-palladium(II) chloride; tri-n-butyl-tin hydride; sodium bis(2-methoxyethoxy)aluminium dihydride; lithium hexamethyldisilazane; acetylene; 2,2'-azobis(isobutyronitrile); copper; palladium; In tetrahydrofuran; triethylamine; toluene;
DOI:10.1016/S0040-4039(00)80037-4