(S)-2-(4-Amino-3-fluoro-phenoxycarbonylamino)-pentanedioic acid di-tert-butyl ester

Base Information

Chemical Name:(S)-2-(4-Amino-3-fluoro-phenoxycarbonylamino)-pentanedioic acid di-tert-butyl ester
CAS No.:1055030-60-8
Molecular Formula:C₂₀H₂₉FN₂O₆
Molecular Weight:412.458
Hs Code.:

Synonyms:(S)-2-(4-Amino-3-fluoro-phenoxycarbonylamino)-pentanedioic acid di-tert-butyl ester

Suppliers and Price of (S)-2-(4-Amino-3-fluoro-phenoxycarbonylamino)-pentanedioic acid di-tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-(4-Amino-3-fluoro-phenoxycarbonylamino)-pentanedioic acid di-tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-(4-Amino-3-fluoro-phenoxycarbonylamino)-pentanedioic acid di-tert-butyl ester

There total 2 articles about (S)-2-(4-Amino-3-fluoro-phenoxycarbonylamino)-pentanedioic acid di-tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 172974-16-2
di-tert-butyl <<(3-fluoro-4-nitrophenyl)oxy>carbonyl>-L-glutamate

: 1055030-60-8
(S)-2-(4-Amino-3-fluoro-phenoxycarbonylamino)-pentanedioic acid di-tert-butyl ester

Guidance literature:: With ammonium formate; palladium on activated charcoal; In ethanol; Ambient temperature;
DOI:10.1021/jm00026a013

Reference yield:

: 32677-01-3
L-glutamic acid di-tert-butyl ester hydrochloride

: 1055030-60-8
(S)-2-(4-Amino-3-fluoro-phenoxycarbonylamino)-pentanedioic acid di-tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 40 percent / Et₃N / CHCl₃ / 5 h / Ambient temperature

2: ammonium formate / 10percent Pd/C / ethanol / Ambient temperature

With ammonium formate; triethylamine; palladium on activated charcoal; In ethanol; chloroform;
DOI:10.1021/jm00026a013

Reference yield:

: 1055030-60-8
(S)-2-(4-Amino-3-fluoro-phenoxycarbonylamino)-pentanedioic acid di-tert-butyl ester

: (S)-2-{4-[Bis-(2-bromo-ethyl)-amino]-3-fluoro-phenoxycarbonylamino}-pentanedioic acid

Guidance literature:: Multi-step reaction with 4 steps

1: AcOH / Ambient temperature

2: pyridine / 2 °C

3: 52 percent / LiBr / acetonitrile / 70 °C

4: 93 percent / TFA / 0.5 h / Ambient temperature

With pyridine; acetic acid; trifluoroacetic acid; lithium bromide; In acetonitrile;
DOI:10.1021/jm00026a013