1-(2-phenoxy-ethyl)-3-(2-piperidin-1-yl-ethyl)-1,3-dihydro-benzoimidazol-2-ylideneamine

Base Information

• Chemical Name: 1-(2-phenoxy-ethyl)-3-(2-piperidin-1-yl-ethyl)-1,3-dihydro-benzoimidazol-2-ylideneamine
• CAS No.: 450353-87-4
• Molecular Formula: C₂₂H₂₈N₄O
• Molecular Weight: 364.491
• Mol file: 450353-87-4.mol

Synonyms:1-(2-phenoxy-ethyl)-3-(2-piperidin-1-yl-ethyl)-1,3-dihydro-benzoimidazol-2-ylideneamine

Chemical Property of 1-(2-phenoxy-ethyl)-3-(2-piperidin-1-yl-ethyl)-1,3-dihydro-benzoimidazol-2-ylideneamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2-phenoxy-ethyl)-3-(2-piperidin-1-yl-ethyl)-1,3-dihydro-benzoimidazol-2-ylideneamine

There total 3 articles about 1-(2-phenoxy-ethyl)-3-(2-piperidin-1-yl-ethyl)-1,3-dihydro-benzoimidazol-2-ylideneamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1H-benzimidazol-2-amine (934-32-7) → 1-(2-phenoxy-ethyl)-3-(2-piperidin-1-yl-ethyl)-1,3-dihydro-benzoimidazol-2-ylideneamine (450353-87-4)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / ethanol / Heating

2: butan-2-one / 48 h / Heating

With potassium hydroxide; In ethanol; butanone;

DOI:10.1016/j.bmcl.2006.11.090

Reference yield:

N-chloroethylpiperidine hydrochloride (2008-75-5) → 1-(2-phenoxy-ethyl)-3-(2-piperidin-1-yl-ethyl)-1,3-dihydro-benzoimidazol-2-ylideneamine (450353-87-4)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / ethanol / Heating

2: butan-2-one / 48 h / Heating

With potassium hydroxide; In ethanol; butanone;

DOI:10.1016/j.bmcl.2006.11.090

Reference yield:

phenoxyethyl bromide (589-10-6) + 2-Amino-1-piperidinoethylbenzimidazole (26840-46-0) → 1-(2-phenoxy-ethyl)-3-(2-piperidin-1-yl-ethyl)-1,3-dihydro-benzoimidazol-2-ylideneamine (450353-87-4)

Guidance literature:

In butanone; for 48h; Heating;

DOI:10.1016/j.bmcl.2006.11.090

upstream raw materials:

phenoxyethyl bromide

2-Amino-1-piperidinoethylbenzimidazole

1H-benzimidazol-2-amine

N-chloroethylpiperidine hydrochloride