2-CHLORO-4-METHYLBENZENESULFONYL CHLORIDE

Base Information

• Chemical Name: 2-CHLORO-4-METHYLBENZENESULFONYL CHLORIDE
• CAS No.: 55311-94-9
• Molecular Formula: C7H6Cl2O2S
• Molecular Weight: 225.095
• Hs Code.: 2904909090
• Mol file: 55311-94-9.mol

Synonyms:3-Chlor-toluol-4-sulfonylchlorid;2-Chloro-4-methylbenzene-1-sulfonyl chloride;2-chloro-p-toluenesulfonyl chloride;2-chloro-4-toluenesulfonyl chloride;3-chloro-toluene-4-sulfonyl chloride;

Chemical Property of 2-CHLORO-4-METHYLBENZENESULFONYL CHLORIDE

Chemical Property:

• Vapor Pressure: 0.0015mmHg at 25°C
• Boiling Point: 305.3°C at 760 mmHg
• Flash Point: 138.4°C
• PSA: 42.52000
• Density: 1.458g/cm³
• LogP: 3.65670
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-4-methylbenzenesulfonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Chloro-4-methylbenzenesulfonyl Chloride (cas# 55311-94-9) is a compound useful in organic synthesis.

Technology Process of 2-CHLORO-4-METHYLBENZENESULFONYL CHLORIDE

There total 3 articles about 2-CHLORO-4-METHYLBENZENESULFONYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-chloro-4-methyl-benzenamine (615-65-6) → 2-chloro-4-methylbenzenesulfonyl chloride (55311-94-9)

Guidance literature:

With hydrogenchloride; sulfur dioxide; acetic acid; copper(l) chloride; sodium nitrite; In water; at 0 - 5 ℃; for 4h;

Reference yield:

→ 2-chloro-4-methylbenzenesulfonyl chloride (55311-94-9)

Guidance literature:

DOI:10.1039/jr9360000691

Reference yield:

→ 2-chloro-4-methylbenzenesulfonyl chloride (55311-94-9)

Guidance literature:

upstream raw materials:

2-chloro-4-methyl-benzenamine

Downstream raw materials:

3-chloro-1-methyl-4-(phenylsulfonyl)benzene

C₇H₆ClFO₂S

C₂₇H₂₇ClN₂O₆S

2-(4-(4-(2-chloro-N,4-dimethylphenylsulfonamido)-2-methyl-1H-indol-5-yloxy)-3-methoxyphenyl)acetic acid