3-Amino-5-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carboxaldehyde

Base Information

Chemical Name:3-Amino-5-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carboxaldehyde
CAS No.:120698-05-7
Molecular Formula:C₁₁H₁₀FN₃O
Molecular Weight:219.218
Hs Code.:
DSSTox Substance ID:DTXSID801172846

Synonyms:SCHEMBL21711412;DTXSID801172846;3-Amino-5-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carboxaldehyde;120698-05-7

Suppliers and Price of 3-Amino-5-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carboxaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Amino-5-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carboxaldehyde

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:219.08079011
Heavy Atom Count:16
Complexity:256

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1C(=C(C(=N1)N)C=O)C2=CC=C(C=C2)F

Technology Process of 3-Amino-5-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carboxaldehyde

There total 1 articles about 3-Amino-5-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 120698-04-6
3-Amino-5--1-methyl-pyrazol

: 120698-05-7
3-amino-5-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde

Guidance literature:: With sodium hydroxide; trichlorophosphate; Yield given. Multistep reaction; 1.) 3 h, 70 deg C, 2.) EtOH, 1.5 h, reflux;

Reference yield: 16.0%

: 4-chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidine

: 120698-05-7
3-amino-5-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde

: 3-{[6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-yl]amino}-5-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium phenoxide; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 90 ℃; Inert atmosphere;