(S)-N-((S)-1,1,1-trifluoro-2-phenylbut-3-yn-2-yl)-2-methylprop-2-ylsulfinamide

Base Information

Chemical Name:(S)-N-((S)-1,1,1-trifluoro-2-phenylbut-3-yn-2-yl)-2-methylprop-2-ylsulfinamide
CAS No.:1269535-59-2
Molecular Formula:C₁₄H₁₆F₃NOS
Molecular Weight:303.348
Hs Code.:

Synonyms:(S)-N-((S)-1,1,1-trifluoro-2-phenylbut-3-yn-2-yl)-2-methylprop-2-ylsulfinamide

Suppliers and Price of (S)-N-((S)-1,1,1-trifluoro-2-phenylbut-3-yn-2-yl)-2-methylprop-2-ylsulfinamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-N-((S)-1,1,1-trifluoro-2-phenylbut-3-yn-2-yl)-2-methylprop-2-ylsulfinamide

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Technology Process of (S)-N-((S)-1,1,1-trifluoro-2-phenylbut-3-yn-2-yl)-2-methylprop-2-ylsulfinamide

There total 1 articles about (S)-N-((S)-1,1,1-trifluoro-2-phenylbut-3-yn-2-yl)-2-methylprop-2-ylsulfinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 884595-96-4
(S)-N-tert-butanesulfinyl ketimine

: 1066-54-2
trimethylsilylacetylene

: 1269535-59-2
(S)-N-((S)-1,1,1-trifluoro-2-phenylbut-3-yn-2-yl)-2-methylprop-2-ylsulfinamide

: 1269535-41-2
(S)-N-((R)-1,1,1-trifluoro-2-phenyl-4-(trimethylsilyl)but-3-yn-2-yl)-2-methylprop-2-ylsulfinamide

Guidance literature:: trimethylsilylacetylene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

(S)-N-tert-butanesulfinyl ketimine; With titanium(IV) isopropylate; In tetrahydrofuran; hexane; at -78 - 20 ℃; optical yield given as %de; diastereoselective reaction; Inert atmosphere;
DOI:10.1016/j.tetasy.2010.11.028