tert-butyl 3-(4-chloromethylbenzoylamino)-5-(N'-methyl-N'-phenylhydrazinocarbonyl)thieno[2,3-c]pyrazole-1-carboxylate

Base Information

• Chemical Name: tert-butyl 3-(4-chloromethylbenzoylamino)-5-(N'-methyl-N'-phenylhydrazinocarbonyl)thieno[2,3-c]pyrazole-1-carboxylate
• CAS No.: 909252-80-8
• Molecular Formula: C₂₆H₂₆ClN₅O₄S
• Molecular Weight: 540.043
• Mol file: 909252-80-8.mol

Synonyms:tert-butyl 3-(4-chloromethylbenzoylamino)-5-(N'-methyl-N'-phenylhydrazinocarbonyl)thieno[2,3-c]pyrazole-1-carboxylate

Chemical Property of tert-butyl 3-(4-chloromethylbenzoylamino)-5-(N'-methyl-N'-phenylhydrazinocarbonyl)thieno[2,3-c]pyrazole-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl 3-(4-chloromethylbenzoylamino)-5-(N'-methyl-N'-phenylhydrazinocarbonyl)thieno[2,3-c]pyrazole-1-carboxylate

There total 1 articles about tert-butyl 3-(4-chloromethylbenzoylamino)-5-(N'-methyl-N'-phenylhydrazinocarbonyl)thieno[2,3-c]pyrazole-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-(chloromethyl)benzoyl chloride (876-08-4) + tert-butyl 3-amino-5-(N'-methyl-N'-phenylhydrazinocarbonyl)-thieno[2,3-c]pyrazole-1-carboxylate (909252-69-3) + tert-butyl 3-amino-5-(N'-(4-chlorophenyl)-N'-methylhydrazinocarbonyl)thieno[2,3-c]pyrazole-1-carboxylate (909252-82-0) → tert-butyl 3-(4-chloromethylbenzoylamino)-5-(N'-methyl-N'-phenylhydrazinocarbonyl)thieno[2,3-c]pyrazole-1-carboxylate (909252-80-8) + tert-butyl 3-(4-chloromethylbenzoylamino)-5-(N'-(4-chlorophenyl)-N'-methylhydrazinocarbonyl)thieno[2,3-c]pyrazole-1-carboxylate (909252-81-9)

Guidance literature:

With potassium carbonate; In tetrahydrofuran; at 25 ℃; for 18h; Heating / reflux;

Reference yield:

1-Methylhomopiperazine (4318-37-0) + tert-butyl 3-(4-chloromethylbenzoylamino)-5-(N'-methyl-N'-phenylhydrazinocarbonyl)thieno[2,3-c]pyrazole-1-carboxylate (909252-80-8) + tert-butyl 3-(4-chloromethylbenzoylamino)-5-(N'-(4-chlorophenyl)-N'-methylhydrazinocarbonyl)thieno[2,3-c]pyrazole-1-carboxylate (909252-81-9) → C32H39N7O4S + C32H38ClN7O4S

Guidance literature:

With tetra-(n-butyl)ammonium iodide; In N,N-dimethyl-formamide; at 25 ℃; for 16h;

Reference yield:

tert-butyl 3-(4-chloromethylbenzoylamino)-5-(N'-methyl-N'-phenylhydrazinocarbonyl)thieno[2,3-c]pyrazole-1-carboxylate (909252-80-8) + tert-butyl 3-(4-chloromethylbenzoylamino)-5-(N'-(4-chlorophenyl)-N'-methylhydrazinocarbonyl)thieno[2,3-c]pyrazole-1-carboxylate (909252-81-9) + N-methylaniline (100-61-8) → C33H34N6O4S

Guidance literature:

With tetra-(n-butyl)ammonium iodide; In N,N-dimethyl-formamide; at 25 ℃; for 360h;

upstream raw materials:

p-(chloromethyl)benzoyl chloride

tert-butyl 3-amino-5-(N'-methyl-N'-phenylhydrazinocarbonyl)-thieno[2,3-c]pyrazole-1-carboxylate

tert-butyl 3-amino-5-(N'-(4-chlorophenyl)-N'-methylhydrazinocarbonyl)thieno[2,3-c]pyrazole-1-carboxylate