O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(1->3)-4-O-benzyl-6-O-(triisopropylsilyl)-D-galactal

Base Information

• Chemical Name: O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(1->3)-4-O-benzyl-6-O-(triisopropylsilyl)-D-galactal
• CAS No.: 944064-66-8
• Molecular Formula: C₅₆H₇₀O₉Si
• Molecular Weight: 915.252
• Mol file: 944064-66-8.mol

Synonyms:O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(1->3)-4-O-benzyl-6-O-(triisopropylsilyl)-D-galactal

Chemical Property of O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(1->3)-4-O-benzyl-6-O-(triisopropylsilyl)-D-galactal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(1->3)-4-O-benzyl-6-O-(triisopropylsilyl)-D-galactal

There total 4 articles about O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(1->3)-4-O-benzyl-6-O-(triisopropylsilyl)-D-galactal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-O-acetyl-3,4,6-tri-O-benzyl-D-galactopyranosyl trichloroacetimidate → O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(1->3)-4-O-benzyl-6-O-(triisopropylsilyl)-D-galactal (944064-66-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / tin (II) triflate / CH₂Cl₂; acetonitrile / 0 °C

2: sodium methanolate / methanol

3: 1.4 g / sodium hydride / dimethylformamide / 16 h

With sodium methylate; sodium hydride; tin (II) triflate; In methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1021/jo061670b

Reference yield:

1,5-anhydro-6-O-triisopropylsilyl-2-deoxy-D-lyxo-hex-1-enitol (166021-01-8) → O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(1->3)-4-O-benzyl-6-O-(triisopropylsilyl)-D-galactal (944064-66-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / tin (II) triflate / CH₂Cl₂; acetonitrile / 0 °C

2: sodium methanolate / methanol

3: 1.4 g / sodium hydride / dimethylformamide / 16 h

With sodium methylate; sodium hydride; tin (II) triflate; In methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1021/jo061670b

Reference yield:

O-(2-O-acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1->3)-6-O-(triisopropylsilyl)-D-galactal (695177-43-6) → O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(1->3)-4-O-benzyl-6-O-(triisopropylsilyl)-D-galactal (944064-66-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium methanolate / methanol

2: 1.4 g / sodium hydride / dimethylformamide / 16 h

With sodium methylate; sodium hydride; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/jo061670b

upstream raw materials:

benzyl bromide

1,5-anhydro-6-O-triisopropylsilyl-2-deoxy-D-lyxo-hex-1-enitol

O-(2-O-acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1->3)-6-O-(triisopropylsilyl)-D-galactal

Downstream raw materials:

O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(1->3)-4-O-benzyl-D-galactal

O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(1->3)-4-O-benzyl-2-nitro-6-O-(triisopropylsilyl)-D-galactal

O-(2-O-azido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranosyl)-(1->6)-[O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(1->3)]-4-O-benzyl-2-nitro-D-galactal

O-(2-O-azido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranosyl)-(1->6)-[O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(1->3)]-4-O-benzyl-D-galactal