Technology Process of diethyl 6-(benzyloxy)-3-hydroxybenzofuran-2,2(3H)-dicarboxylate
There total 1 articles about diethyl 6-(benzyloxy)-3-hydroxybenzofuran-2,2(3H)-dicarboxylate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
acetone;
at 20 ℃;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 85.6 percent / H2, conc. H2SO4 / 10percent Pd/C / acetic acid / 2280 Torr / Ambient temperature
2: 9.6 g / BF3*Et2O, Ac2O / 19 h / 120 °C
3: BF3*Et2O / 17 h / Heating
4: 67.6 percent / K2CO3 / 18-crown-6 / acetonitrile / 22 h / Heating
5: 78.8 percent / K2CO3 / acetone; dimethylformamide / 5.5 h / Heating
6: 74.8 percent / KOH / methanol / 3 h / Ambient temperature
With
potassium hydroxide; sulfuric acid; boron trifluoride diethyl etherate; hydrogen; acetic anhydride; potassium carbonate;
palladium on activated charcoal; 18-crown-6 ether;
In
methanol; acetic acid; N,N-dimethyl-formamide; acetone; acetonitrile;
DOI:10.1021/jm00128a028
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 85.6 percent / H2, conc. H2SO4 / 10percent Pd/C / acetic acid / 2280 Torr / Ambient temperature
2: 9.6 g / BF3*Et2O, Ac2O / 19 h / 120 °C
3: BF3*Et2O / 17 h / Heating
4: 67.6 percent / K2CO3 / 18-crown-6 / acetonitrile / 22 h / Heating
5: 78.8 percent / K2CO3 / acetone; dimethylformamide / 5.5 h / Heating
With
sulfuric acid; boron trifluoride diethyl etherate; hydrogen; acetic anhydride; potassium carbonate;
palladium on activated charcoal; 18-crown-6 ether;
In
acetic acid; N,N-dimethyl-formamide; acetone; acetonitrile;
DOI:10.1021/jm00128a028
