C₄₂H₅₇NO₉

Base Information

• Chemical Name: C₄₂H₅₇NO₉
• CAS No.: 474125-41-2
• Molecular Formula: C₄₂H₅₇NO₉
• Molecular Weight: 719.916
• Mol file: 474125-41-2.mol

Synonyms:C₄₂H₅₇NO₉

Chemical Property of C₄₂H₅₇NO₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₂H₅₇NO₉

There total 31 articles about C₄₂H₅₇NO₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C46H60O8 (253172-09-7) → C42H57NO9 (474125-41-2)

Guidance literature:

Multi-step reaction with 6 steps

1: 99 percent / hydrogen; AcOH / Pd(OH)2/C / ethyl acetate; methanol / 72 h / 20 °C

2: 174 mg / 10-camphorsulfonic acid / tetrahydrofuran / 1 h / 20 °C

3: 100 percent / N,N-diisopropylethylamine / 1,2-dichloro-ethane / 14 h / 40 °C

4: 100 percent / diisobutylaluminum hydride / CH₂Cl₂; hexane / 1.58 h / -80 - -40 °C

5: triethylamine / 1,2-dichloro-ethane / 0.67 h / 0 °C

6: 202 mg / 18-crown-6 / dimethylformamide / 48 h / 50 °C

With 18-crown-6 ether; (1S)-10-camphorsulfonic acid; hydrogen; diisobutylaluminium hydride; acetic acid; triethylamine; N-ethyl-N,N-diisopropylamine; palladium dihydroxide; In tetrahydrofuran; methanol; hexane; dichloromethane; ethyl acetate; 1,2-dichloro-ethane; N,N-dimethyl-formamide;

DOI:10.1016/S0040-4020(02)00660-9

Reference yield:

sodium cyanide (143-33-9,25596-52-5) + C42H60O12S → C42H57NO9 (474125-41-2)

Guidance literature:

With 18-crown-6 ether; In N,N-dimethyl-formamide; at 50 ℃; for 48h;

DOI:10.1016/S0040-4020(02)00660-9

Reference yield:

C25H42O8 (337309-27-0) → C42H57NO9 (474125-41-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 174 mg / 10-camphorsulfonic acid / tetrahydrofuran / 1 h / 20 °C

2: 100 percent / N,N-diisopropylethylamine / 1,2-dichloro-ethane / 14 h / 40 °C

3: 100 percent / diisobutylaluminum hydride / CH₂Cl₂; hexane / 1.58 h / -80 - -40 °C

4: triethylamine / 1,2-dichloro-ethane / 0.67 h / 0 °C

5: 202 mg / 18-crown-6 / dimethylformamide / 48 h / 50 °C

With 18-crown-6 ether; (1S)-10-camphorsulfonic acid; diisobutylaluminium hydride; triethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; hexane; dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide;

DOI:10.1016/S0040-4020(02)00660-9

upstream raw materials:

sodium cyanide

(3S,4S,5R,6S)-6-Benzyloxymethyl-5-hydroxy-3,4-dimethyl-tetrahydro-pyran-2-one

(3S,4S,5S)-5-((R)-2-Benzyloxy-1-iodo-ethyl)-3,4-dimethyl-dihydro-furan-2-one

(5R,7R,8R,9S,10S)-8-Methoxymethoxy-9,10-dimethyl-1,6-dioxa-spiro[4.5]decane-7-carbaldehyde

Downstream raw materials:

C₄₅H₆₄O₁₀

C₄₆H₆₄O₁₀

C₄₅H₆₄O₁₁

C₄₇H₆₆O₁₁