4-Piperidinol, 4-(4-chlorophenyl)-1-(4-((7-(trifluoromethyl)-4-quinolinyl)amino)benzoyl)-

Base Information

Chemical Name:4-Piperidinol, 4-(4-chlorophenyl)-1-(4-((7-(trifluoromethyl)-4-quinolinyl)amino)benzoyl)-
CAS No.:71916-54-6
Molecular Formula:C₂₈H₂₃ClF₃N₃O₂
Molecular Weight:525.958
Hs Code.:
DSSTox Substance ID:DTXSID40222168
Wikidata:Q83100338
ChEMBL ID:CHEMBL29998

Synonyms:BRN 0467362;4-Piperidinol, 4-(4-chlorophenyl)-1-(4-((7-(trifluoromethyl)-4-quinolinyl)amino)benzoyl)-;4-(4-Chlorophenyl)-1-(4-((7-(trifluoromethyl)-4-quinolinyl)amino)benzoyl)-4-piperidinol;71916-54-6;C28H23ClF3N3O2;CHEMBL29998;SCHEMBL11521928;DTXSID40222168;AZWPXPDYMDKHIC-UHFFFAOYSA-N;C28-H23-Cl-F3-N3-O2;LS-116930

Suppliers and Price of 4-Piperidinol, 4-(4-chlorophenyl)-1-(4-((7-(trifluoromethyl)-4-quinolinyl)amino)benzoyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-Piperidinol, 4-(4-chlorophenyl)-1-(4-((7-(trifluoromethyl)-4-quinolinyl)amino)benzoyl)-

Chemical Property:

Vapor Pressure:3.77E-19mmHg at 25°C
Boiling Point:675.1°Cat760mmHg
Flash Point:362.1°C
Density:1.41g/cm³
XLogP3:5.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:525.1430892
Heavy Atom Count:37
Complexity:775

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1(C2=CC=C(C=C2)Cl)O)C(=O)C3=CC=C(C=C3)NC4=C5C=CC(=CC5=NC=C4)C(F)(F)F

Technology Process of 4-Piperidinol, 4-(4-chlorophenyl)-1-(4-((7-(trifluoromethyl)-4-quinolinyl)amino)benzoyl)-

There total 5 articles about 4-Piperidinol, 4-(4-chlorophenyl)-1-(4-((7-(trifluoromethyl)-4-quinolinyl)amino)benzoyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 71916-45-5
4-<<7-(trifluoromethyl)-4-quinolinyl>amino>benzoic acid

: 530-62-1
1,1'-carbonyldiimidazole

: 857027-07-7
imidazolide

: 71916-54-6
4-(4-chlorophenyl)-1-<4-<<7-(trifluoromethyl)-4-quinolinyl>amino>benzoyl>piperidinol

Guidance literature:

Reference yield:

: 346-55-4
4-chloro-7-trifluoromethyl quinoline

: 71916-54-6
4-(4-chlorophenyl)-1-<4-<<7-(trifluoromethyl)-4-quinolinyl>amino>benzoyl>piperidinol

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / 4 h / Heating

2: dimethylformamide / 1 h

3: dimethylformamide / 20 h

In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00151a021

Reference yield:

: 150-13-0,159246-81-8,8014-65-1
4-amino-benzoic acid

: 71916-54-6
4-(4-chlorophenyl)-1-<4-<<7-(trifluoromethyl)-4-quinolinyl>amino>benzoyl>piperidinol

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / 4 h / Heating

2: dimethylformamide / 1 h

3: dimethylformamide / 20 h

In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00151a021