Phenol, 4-[(phenylimino)methyl]-

Base Information

• Chemical Name: Phenol, 4-[(phenylimino)methyl]-
• CAS No.: 1689-73-2
• Molecular Formula: C13H11 N O
• Molecular Weight: 197.236
• European Community (EC) Number: 683-590-8
• NSC Number: 32434
• UNII: GNE5J446UD
• DSSTox Substance ID: DTXSID9061885
• Nikkaji Number: J102.243A
• ChEMBL ID: CHEMBL1091624
• Mol file: 1689-73-2.mol

Synonyms:1689-73-2;4-((phenylimino)methyl)phenol;Phenol, 4-[(phenylimino)methyl]-;4-Hydroxybenzalaniline;N-(p-Hydroxybenzylidene)aniline;4-(Phenyliminomethyl)phenol;N-p-Hydroxybenzalaniline;1-(4-Hydroxybenzylidene) aniline;Phenol, p-(N-phenylformimidoyl)-;Phenol, 4-((phenylimino)methyl)-;CHEMBL1091624;NSC 32434;NSC-32434;4-[(PHENYLIMINO)METHYL]PHENOL;4-(anilinomethylidene)cyclohexa-2,5-dien-1-one;NSC32434;4-hydroxybenzal aniline;alpha-Phenylimino-p-cresol;4-hydroxybenzylidene-aniline;TimTec1_001269;GNE5J446UD;CBDivE_002073;2505-66-0;4-(N-phenylformimidoyl)phenol;SCHEMBL2311078;N-(4-hydroxybenzylidene)aniline;DTXSID9061885;HMS1537J15;4-[(E)-(Phenylimino)methyl]phenol;BDBM50529601;MFCD00029728;AKOS003672104;AKOS003808183;AKOS016038554;4-[(E)-(Phenylimino)methyl]phenol #;NCGC00174610-01;BS-50558;CS-0164723;E76485;BRD-K20643289-001-01-8;(E)-4-((phenylimino)methyl)phenol? (Ezetimibe Impurity pound(c)

Chemical Property of Phenol, 4-[(phenylimino)methyl]-

Chemical Property:

• Vapor Pressure: 5.4E-05mmHg at 25°C
• Melting Point: 195 °C
• Boiling Point: 347.4°C at 760 mmHg
• PKA: 8.74±0.13(Predicted)
• Flash Point: 145°C
• PSA: 32.59000
• Density: 1.279g/cm³
• LogP: 3.14280
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 197.084063974
• Heavy Atom Count: 15
• Complexity: 201

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)N=CC2=CC=C(C=C2)O

Technology Process of Phenol, 4-[(phenylimino)methyl]-

There total 16 articles about Phenol, 4-[(phenylimino)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) + aniline (62-53-3) → N-(p-hydroxybenzylidene)aniline (1689-73-2)

Guidance literature:

In ethyl 2-hydroxypropionate; water; at 20 ℃; for 0.116667h;

DOI:10.1039/b817379f

Reference yield: 99.0%

→ N-(p-hydroxybenzylidene)aniline (1689-73-2)

Guidance literature:

Reference yield: 84.0%

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) + aniline (62-53-3) → N-(p-hydroxybenzylidene)aniline (1689-73-2,40339-46-6,2505-66-0)

Guidance literature:

With acetic acid; In toluene; for 24h; pH=4 - 5; Reflux;

DOI:10.1016/j.molstruc.2016.03.028

upstream raw materials:

4-hydroxy-benzaldehyde

aniline

N-benzylidene-4-bromoaniline

p-hydroxy benzylidene 2-aminobenzothiazole

Downstream raw materials:

4-[1-(3-nitro-phenyl)-3,4-diphenyl-[1,3]diazetidin-2-yl]-phenol

4-[1-(4-bromo-phenyl)-3,4-diphenyl-[1,3]diazetidin-2-yl]-phenol

α-anilino-p-quinone methide hydrochloride

1-(4-phenyliminomethyl-phenoxymethyl)benzo[f]chromen-3-one

Refernces

• 1、 Elemike, Elias E.,Nwankwo, Henry U.,Onwudiwe, Damian C.. "Synthesis and comparative study on the anti-corrosion potentials of some Schiff base compounds bearing similar backbone". . p. 233 - 242. Retrieved 2019.
• 2、 Mal, Diptangshu Datta,Pradhan, Debabrata. "Room Temperature Acid-Free Greener Synthesis of Imine Using Cobalt-Doped Manganese Tungstate". . p. 2211 - 2218. Retrieved 2022/01/31.
• 3、 Dutra, Rafael Cypriano,Goliatt, Priscila Vanessa Zabala Capriles,Marion, Gabriel Macedo,Meinel, Raissa Soares,Nunes, Vinicius Schmitz Pereira,da Silva, Adilson David,Fávero, Amanda,Menegasso, Jaíne Ferrareis,Raposo, Nádia Rezende Barbosa,de Assis, Pollyana Mendon?a. "In silico, in vitro and in vivo studies indicate resveratrol analogue as a potential alternative for neuroinflammatory disorders". . . Retrieved 2020/03/18.