4-{3-[4-(3-{4-[amino(imino)methyl]phenoxy)propyl)-1-piperazinyl]propoxy}benzamidine

Base Information

Chemical Name:4-{3-[4-(3-{4-[amino(imino)methyl]phenoxy)propyl)-1-piperazinyl]propoxy}benzamidine
CAS No.:596809-49-3
Molecular Formula:C₂₄H₃₄N₆O₂
Molecular Weight:438.573
Hs Code.:

Synonyms:4-{3-[4-(3-{4-[amino(imino)methyl]phenoxy)propyl)-1-piperazinyl]propoxy}benzamidine

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Chemical Property of 4-{3-[4-(3-{4-[amino(imino)methyl]phenoxy)propyl)-1-piperazinyl]propoxy}benzamidine

Chemical Property:

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Technology Process of 4-{3-[4-(3-{4-[amino(imino)methyl]phenoxy)propyl)-1-piperazinyl]propoxy}benzamidine

There total 2 articles about 4-{3-[4-(3-{4-[amino(imino)methyl]phenoxy)propyl)-1-piperazinyl]propoxy}benzamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-{3-[4-(3-{4-[amino(hydroxyimino)methyl]phenoxy}propyl)-1-piperazinyl]propoxy}-N'-hydroxybenzamidine

: 596809-49-3
4-{3-[4-(3-{4-[amino(imino)methyl]phenoxy)propyl)-1-piperazinyl]propoxy}benzamidine

Guidance literature:: 4-{3-[4-(3-{4-[amino(hydroxyimino)methyl]phenoxy}propyl)-1-piperazinyl]propoxy}-N'-hydroxybenzamidine; With acetic anhydride; In acetic acid; at 20 ℃; for 1h;

With hydrogen; 5%-palladium/activated carbon; In acetic acid; at 20 ℃; for 1.5h; under 760.051 Torr;

Reference yield:

: 596810-17-2
4-(3-(4-[3-(4-cyanophenoxy)propyl]-1-piperazinyl}propoxy)benzonitrile

: 596809-49-3
4-{3-[4-(3-{4-[amino(imino)methyl]phenoxy)propyl)-1-piperazinyl]propoxy}benzamidine

Guidance literature:: 4-(3-(4-[3-(4-cyanophenoxy)propyl]-1-piperazinyl}propoxy)benzonitrile; With hydrogenchloride; In ethanol; at 0 - 20 ℃; for 48h;

With ammonium acetate; In ethanol; at 20 ℃; for 6h; Heating / reflux;

Reference yield:

: 596809-49-3
4-{3-[4-(3-{4-[amino(imino)methyl]phenoxy)propyl)-1-piperazinyl]propoxy}benzamidine

: 14009-94-0
N-acetyl-L-phenylalanine 4-nitrophenyl ester

: (2S)-2-(acetylamino)-N-[(4-{3-[4-(3-{4-[{[(2S)-2-(acetylamino)-3-phenylpropanoyl]amino}(imino)methyl]phenoxy}propyl)-1-piperazinyl]propoxy}phenyl)(imino)methyl]-3-phenylpropanamide hydrochloride

Guidance literature:: 4-{3-[4-(3-{4-[amino(imino)methyl]phenoxy)propyl)-1-piperazinyl]propoxy}benzamidine; N-acetyl-L-phenylalanine 4-nitrophenyl ester; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 12h;

With hydrogenchloride; In ethanol; at 20 ℃;