(1R,3R)-methyl 3-(5-(5-(3,4-difluorophenylamino)-1,3,4-oxadiazole-2-carboxamido)pyridin-2-yloxy)cyclopentanecarboxylate

Base Information

Chemical Name:(1R,3R)-methyl 3-(5-(5-(3,4-difluorophenylamino)-1,3,4-oxadiazole-2-carboxamido)pyridin-2-yloxy)cyclopentanecarboxylate
CAS No.:1124174-64-6
Molecular Formula:C₂₁H₁₉F₂N₅O₅
Molecular Weight:459.409
Hs Code.:

Synonyms:(1R,3R)-methyl 3-(5-(5-(3,4-difluorophenylamino)-1,3,4-oxadiazole-2-carboxamido)pyridin-2-yloxy)cyclopentanecarboxylate

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Chemical Property of (1R,3R)-methyl 3-(5-(5-(3,4-difluorophenylamino)-1,3,4-oxadiazole-2-carboxamido)pyridin-2-yloxy)cyclopentanecarboxylate

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Technology Process of (1R,3R)-methyl 3-(5-(5-(3,4-difluorophenylamino)-1,3,4-oxadiazole-2-carboxamido)pyridin-2-yloxy)cyclopentanecarboxylate

There total 1 articles about (1R,3R)-methyl 3-(5-(5-(3,4-difluorophenylamino)-1,3,4-oxadiazole-2-carboxamido)pyridin-2-yloxy)cyclopentanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1124174-65-7
(1R,3R)-methyl 3-(5-(2-hydrazinyl-2-oxoacetamido)pyridin-2-yloxy)cyclopentanecarboxylate

: 113028-75-4
3,4-difluorophenyl isothiocyanate

: 1124174-64-6
(1R,3R)-methyl 3-(5-(5-(3,4-difluorophenylamino)-1,3,4-oxadiazole-2-carboxamido)pyridin-2-yloxy)cyclopentanecarboxylate

Guidance literature:: (1R,3R)-methyl 3-(5-(2-hydrazinyl-2-oxoacetamido)pyridin-2-yloxy)cyclopentanecarboxylate; 3,4-difluorophenyl isothiocyanate; In N,N-dimethyl-formamide; at 55 ℃; for 1h;

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 55 - 85 ℃; for 2h;

Reference yield:

: 1124174-64-6
(1R,3R)-methyl 3-(5-(5-(3,4-difluorophenylamino)-1,3,4-oxadiazole-2-carboxamido)pyridin-2-yloxy)cyclopentanecarboxylate

: 1124173-13-2
(1R,3R)-3-(5-(5-(3,4-difluorophenylamino)-1,3,4-oxadiazole-2-carboxamido)pyridin-2-yloxy)cyclopentanecarboxylic acid

Guidance literature:: (1R,3R)-methyl 3-(5-(5-(3,4-difluorophenylamino)-1,3,4-oxadiazole-2-carboxamido)pyridin-2-yloxy)cyclopentanecarboxylate; With sodium hydroxide; water; In methanol; for 16h;

With hydrogenchloride; In water;